New‐generation fish oil and olive oil lipid for prevention of oxidative damage in preterm infants: Single center clinical trial at university hospital in Turkey

Background Parenteral nutrition (PN) has been widely used in preterm infants. The lipid solutions used for PN, however, are associated with oxidative stress and morbidity. The aim of this study was to compare the effectiveness of a new‐generation lipid emulsion (SMOFLipid) and olive‐oil based lipid emulsion for prevention of PN‐associated oxidative damage. Methods Preterm infants 0.05. The rate of severe BPD was significantly lower in the SMOFlipid group. Conclusion To our best of knowledge, this is the first study to suggest that SMOFlipid might decrease oxidative damage and oxidative‐stress‐associated morbidity compared with olive oil‐based emulsion in preterm infants.