A three-component supramolecular nanocomposite as a heavy-atom-free photosensitizer

A three-component supramolecular nanocomposite as a heavy-atom-free photosensitizer

Design of photosensitizers capable of generating singlet oxygen is crucial for the success of photodynamic therapy, and biocompatible supramolecular systems are emerging in this area. We report a supramolecular nanocomposite consisting of BODIPY, tryptophan and gold nanoparticles. While the individu...

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Veröffentlicht in:Chemical communications (Cambridge, England) England), 2019-05, Vol.55 (39), p.5623-5626
Hauptverfasser: Kumar, P P Praveen, Yadav, Pranjali, Shanavas, Asifkhan, Thurakkal, Shameel, Joseph, Joshy, Neelakandan, Prakash P
Format: Artikel
Sprache:eng
Schlagworte:
Biocompatibility
Gold
Nanocomposites
Nanoparticles
Photodynamic therapy
Singlet oxygen
Tryptophan
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Zusammenfassung:Design of photosensitizers capable of generating singlet oxygen is crucial for the success of photodynamic therapy, and biocompatible supramolecular systems are emerging in this area. We report a supramolecular nanocomposite consisting of BODIPY, tryptophan and gold nanoparticles. While the individual components in isolation were inactive, the nanocomposite was found to be photostable and exhibited efficient photosensitization properties.
ISSN:1359-7345
1364-548X
DOI:10.1039/c9cc02480h