Outcomes of preterm infants conceived with in vitro fertilization

Objectives To determine if there is increased risk of prematurity-related complications for in vitro fertilization (IVF)-conceived preterm infants compared to matched controls. Study Design Cohort study of 23–34 weeks’ preterm infants from 329 US NICUs discharged from 2009 to 2016. Each IVF patient...

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Veröffentlicht in:Journal of perinatology 2019-05, Vol.39 (5), p.717-722
Hauptverfasser: Ahmad, Kaashif Aqeeb, Bennett, Monica M., Rayburn, Polli, Combs, C. Andrew, Clark, Reese H., Tolia, Veeral N.
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Sprache:eng
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Zusammenfassung:Objectives To determine if there is increased risk of prematurity-related complications for in vitro fertilization (IVF)-conceived preterm infants compared to matched controls. Study Design Cohort study of 23–34 weeks’ preterm infants from 329 US NICUs discharged from 2009 to 2016. Each IVF patient was matched to three controls. Results We identified 6,756 IVF-conceived preterm infants who were matched with 20,268 controls. IVF-conceived infants had no increase in non-respiratory morbidities but had significantly higher rates of bronchopulmonary dysplasia (8.4% vs 7%, p  
ISSN:0743-8346
1476-5543
DOI:10.1038/s41372-019-0332-y