Do dental bleaching agents induce genetic damage on oral mucosa cells?

We have read with interest your letter and we are here in providing answers for your concerns. The author questioned the use of Giemsa as staining method. Giemsa technique has been criticized because it is not a specific staining technique for DNA which could result in a low specificity of the test compared to DNAspecific staining tests [1]. However, the literature shows that many studies use Giemsa staining [2–6] to evaluate micronuclei frequency