Correlations between mitochondrial respiration activity and residual feed intake after divergent genetic selection for high‐ and low‐ oxygen consumption in mice

The aims of the present study were to identify the differences between two mouse lines (high (H)‐ and low (L)‐oxygen consumption) in terms of mitochondrial respiratory activity when GMP (glutamate, malate, and pyruvate) and succinic acid are used as substrates and to examine the relationship between...

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Veröffentlicht in:Animal science journal 2019-07, Vol.90 (7), p.818-826
Hauptverfasser: Darhan, Hongyu, Zoda, Atsushi, Kikusato, Motoi, Toyomizu, Masaaki, Katoh, Kazuo, Roh, Sang‐gun, Ogawa, Shinichiro, Uemoto, Yoshinobu, Satoh, Masahiro, Suzuki, Keiichi
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Sprache:eng
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Zusammenfassung:The aims of the present study were to identify the differences between two mouse lines (high (H)‐ and low (L)‐oxygen consumption) in terms of mitochondrial respiratory activity when GMP (glutamate, malate, and pyruvate) and succinic acid are used as substrates and to examine the relationship between mitochondrial respiration activity and feed efficiency in both lines. The average daily feed intake, feed conversion ratio (FCR), and residual feed intake (RFI) were significantly higher in the H than the L line. The correlation between FCR and RFI was significant (r = 0.60, p 
ISSN:1344-3941
1740-0929
DOI:10.1111/asj.13210