Muted fibrosis from protected islets

Transplanting allogeneic pancreatic islets intraperitoneally by first encapsulating the islets within an alginate-based formulation results in reduced fibrosis and capsule clumping, and thus in improved islet survival.

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Nature biomedical engineering 2018-11, Vol.2 (11), p.791-792
Hauptverfasser: Vlahos, Alexander E., Sefton, Michael V.
Format: Artikel
Sprache:eng
Schlagworte:
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page 792
container_issue 11
container_start_page 791
container_title Nature biomedical engineering
container_volume 2
creator Vlahos, Alexander E.
Sefton, Michael V.
description Transplanting allogeneic pancreatic islets intraperitoneally by first encapsulating the islets within an alginate-based formulation results in reduced fibrosis and capsule clumping, and thus in improved islet survival.
doi_str_mv 10.1038/s41551-018-0316-9
format Article
fullrecord <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_2213916014</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2389701731</sourcerecordid><originalsourceid>FETCH-LOGICAL-c415t-2de233ff373babc534834dff9ad90c68fb55ffd84dbe6e35d93858c524a13f9c3</originalsourceid><addsrcrecordid>eNp1kMtKxDAUhoMozqDzAG5kQBduqjk5SZssZfAGI24U3IU2F-nQTsekXfj2Zuh4QXCVkHznz5-PkBOgl0BRXkUOQkBGQWYUIc_UHpkyEEUmef66_2s_IbMYV5RSUMhVIQ7JBIGCyCGfkvPHoXd27usqdLGOcx-6dr4JXe_M9ryOjevjMTnwZRPdbLcekZfbm-fFfbZ8untYXC8zk7r0GbOOIXqPBVZlZQRyidx6r0qrqMmlr4Tw3kpuK5c7FFahFNIIxktArwwekYsxNxV4H1zsdVtH45qmXLtuiJoxQAU5BZ7Qsz_oqhvCOrXTDKUqKBQIiYKRMul3MTivN6Fuy_ChgeqtRT1a1Mmi3lrUKs2c7pKHqnX2e-LLWQLYCMR0tX5z4efp_1M_AV99exY</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2389701731</pqid></control><display><type>article</type><title>Muted fibrosis from protected islets</title><source>SpringerLink Journals - AutoHoldings</source><creator>Vlahos, Alexander E. ; Sefton, Michael V.</creator><creatorcontrib>Vlahos, Alexander E. ; Sefton, Michael V.</creatorcontrib><description>Transplanting allogeneic pancreatic islets intraperitoneally by first encapsulating the islets within an alginate-based formulation results in reduced fibrosis and capsule clumping, and thus in improved islet survival.</description><identifier>ISSN: 2157-846X</identifier><identifier>EISSN: 2157-846X</identifier><identifier>DOI: 10.1038/s41551-018-0316-9</identifier><identifier>PMID: 31015616</identifier><language>eng</language><publisher>London: Nature Publishing Group UK</publisher><subject>692/698/1460/1583 ; 692/699/2743/137 ; 692/700/565/545/576/1955 ; 692/700/565/545/576/2033 ; Alginates ; Alginic acid ; Biomedical and Life Sciences ; Biomedical Engineering/Biotechnology ; Biomedicine ; Fibrosis ; News &amp; Views ; news-and-views ; Pancreas transplantation ; Pancreatic islet transplantation</subject><ispartof>Nature biomedical engineering, 2018-11, Vol.2 (11), p.791-792</ispartof><rights>Springer Nature Limited 2018</rights><rights>Springer Nature Limited 2018.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c415t-2de233ff373babc534834dff9ad90c68fb55ffd84dbe6e35d93858c524a13f9c3</citedby><cites>FETCH-LOGICAL-c415t-2de233ff373babc534834dff9ad90c68fb55ffd84dbe6e35d93858c524a13f9c3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1038/s41551-018-0316-9$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1038/s41551-018-0316-9$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,776,780,27901,27902,41464,42533,51294</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/31015616$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Vlahos, Alexander E.</creatorcontrib><creatorcontrib>Sefton, Michael V.</creatorcontrib><title>Muted fibrosis from protected islets</title><title>Nature biomedical engineering</title><addtitle>Nat Biomed Eng</addtitle><addtitle>Nat Biomed Eng</addtitle><description>Transplanting allogeneic pancreatic islets intraperitoneally by first encapsulating the islets within an alginate-based formulation results in reduced fibrosis and capsule clumping, and thus in improved islet survival.</description><subject>692/698/1460/1583</subject><subject>692/699/2743/137</subject><subject>692/700/565/545/576/1955</subject><subject>692/700/565/545/576/2033</subject><subject>Alginates</subject><subject>Alginic acid</subject><subject>Biomedical and Life Sciences</subject><subject>Biomedical Engineering/Biotechnology</subject><subject>Biomedicine</subject><subject>Fibrosis</subject><subject>News &amp; Views</subject><subject>news-and-views</subject><subject>Pancreas transplantation</subject><subject>Pancreatic islet transplantation</subject><issn>2157-846X</issn><issn>2157-846X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2018</creationdate><recordtype>article</recordtype><sourceid>BENPR</sourceid><recordid>eNp1kMtKxDAUhoMozqDzAG5kQBduqjk5SZssZfAGI24U3IU2F-nQTsekXfj2Zuh4QXCVkHznz5-PkBOgl0BRXkUOQkBGQWYUIc_UHpkyEEUmef66_2s_IbMYV5RSUMhVIQ7JBIGCyCGfkvPHoXd27usqdLGOcx-6dr4JXe_M9ryOjevjMTnwZRPdbLcekZfbm-fFfbZ8untYXC8zk7r0GbOOIXqPBVZlZQRyidx6r0qrqMmlr4Tw3kpuK5c7FFahFNIIxktArwwekYsxNxV4H1zsdVtH45qmXLtuiJoxQAU5BZ7Qsz_oqhvCOrXTDKUqKBQIiYKRMul3MTivN6Fuy_ChgeqtRT1a1Mmi3lrUKs2c7pKHqnX2e-LLWQLYCMR0tX5z4efp_1M_AV99exY</recordid><startdate>20181101</startdate><enddate>20181101</enddate><creator>Vlahos, Alexander E.</creator><creator>Sefton, Michael V.</creator><general>Nature Publishing Group UK</general><general>Nature Publishing Group</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>8FE</scope><scope>8FG</scope><scope>8FH</scope><scope>ABJCF</scope><scope>AFKRA</scope><scope>ARAPS</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BGLVJ</scope><scope>BHPHI</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>GNUQQ</scope><scope>HCIFZ</scope><scope>L6V</scope><scope>LK8</scope><scope>M7P</scope><scope>M7S</scope><scope>P5Z</scope><scope>P62</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>PTHSS</scope><scope>7X8</scope></search><sort><creationdate>20181101</creationdate><title>Muted fibrosis from protected islets</title><author>Vlahos, Alexander E. ; Sefton, Michael V.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c415t-2de233ff373babc534834dff9ad90c68fb55ffd84dbe6e35d93858c524a13f9c3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2018</creationdate><topic>692/698/1460/1583</topic><topic>692/699/2743/137</topic><topic>692/700/565/545/576/1955</topic><topic>692/700/565/545/576/2033</topic><topic>Alginates</topic><topic>Alginic acid</topic><topic>Biomedical and Life Sciences</topic><topic>Biomedical Engineering/Biotechnology</topic><topic>Biomedicine</topic><topic>Fibrosis</topic><topic>News &amp; Views</topic><topic>news-and-views</topic><topic>Pancreas transplantation</topic><topic>Pancreatic islet transplantation</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Vlahos, Alexander E.</creatorcontrib><creatorcontrib>Sefton, Michael V.</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Technology Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Materials Science &amp; Engineering Collection</collection><collection>ProQuest Central UK/Ireland</collection><collection>Advanced Technologies &amp; Aerospace Collection</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Technology Collection</collection><collection>Natural Science Collection</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>ProQuest Central Student</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Engineering Collection</collection><collection>ProQuest Biological Science Collection</collection><collection>Biological Science Database</collection><collection>Engineering Database</collection><collection>Advanced Technologies &amp; Aerospace Database</collection><collection>ProQuest Advanced Technologies &amp; Aerospace Collection</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>Engineering Collection</collection><collection>MEDLINE - Academic</collection><jtitle>Nature biomedical engineering</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Vlahos, Alexander E.</au><au>Sefton, Michael V.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Muted fibrosis from protected islets</atitle><jtitle>Nature biomedical engineering</jtitle><stitle>Nat Biomed Eng</stitle><addtitle>Nat Biomed Eng</addtitle><date>2018-11-01</date><risdate>2018</risdate><volume>2</volume><issue>11</issue><spage>791</spage><epage>792</epage><pages>791-792</pages><issn>2157-846X</issn><eissn>2157-846X</eissn><abstract>Transplanting allogeneic pancreatic islets intraperitoneally by first encapsulating the islets within an alginate-based formulation results in reduced fibrosis and capsule clumping, and thus in improved islet survival.</abstract><cop>London</cop><pub>Nature Publishing Group UK</pub><pmid>31015616</pmid><doi>10.1038/s41551-018-0316-9</doi><tpages>2</tpages><oa>free_for_read</oa></addata></record>
fulltext fulltext
identifier ISSN: 2157-846X
ispartof Nature biomedical engineering, 2018-11, Vol.2 (11), p.791-792
issn 2157-846X
2157-846X
language eng
recordid cdi_proquest_miscellaneous_2213916014
source SpringerLink Journals - AutoHoldings
subjects 692/698/1460/1583
692/699/2743/137
692/700/565/545/576/1955
692/700/565/545/576/2033
Alginates
Alginic acid
Biomedical and Life Sciences
Biomedical Engineering/Biotechnology
Biomedicine
Fibrosis
News & Views
news-and-views
Pancreas transplantation
Pancreatic islet transplantation
title Muted fibrosis from protected islets
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-03T22%3A42%3A09IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Muted%20fibrosis%20from%20protected%20islets&rft.jtitle=Nature%20biomedical%20engineering&rft.au=Vlahos,%20Alexander%20E.&rft.date=2018-11-01&rft.volume=2&rft.issue=11&rft.spage=791&rft.epage=792&rft.pages=791-792&rft.issn=2157-846X&rft.eissn=2157-846X&rft_id=info:doi/10.1038/s41551-018-0316-9&rft_dat=%3Cproquest_cross%3E2389701731%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2389701731&rft_id=info:pmid/31015616&rfr_iscdi=true