Muted fibrosis from protected islets

Transplanting allogeneic pancreatic islets intraperitoneally by first encapsulating the islets within an alginate-based formulation results in reduced fibrosis and capsule clumping, and thus in improved islet survival.

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Bibliographische Detailangaben
Veröffentlicht in:	Nature biomedical engineering 2018-11, Vol.2 (11), p.791-792
Hauptverfasser:	Vlahos, Alexander E., Sefton, Michael V.
Format:	Artikel
Sprache:	eng
Schlagworte:	692/698/1460/1583 692/699/2743/137 692/700/565/545/576/1955 692/700/565/545/576/2033 Alginates Alginic acid Biomedical and Life Sciences Biomedical Engineering/Biotechnology Biomedicine Fibrosis News & Views news-and-views Pancreas transplantation Pancreatic islet transplantation
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Beschreibung
Zusammenfassung:	Transplanting allogeneic pancreatic islets intraperitoneally by first encapsulating the islets within an alginate-based formulation results in reduced fibrosis and capsule clumping, and thus in improved islet survival.
ISSN:	2157-846X 2157-846X
DOI:	10.1038/s41551-018-0316-9