Inhaled Corticosteroids for the Prevention of Bronchopulmonary Dysplasia and Complications of Prematurity

[...]this has been associated with increasing rates of bronchopulmonary dysplasia (BPD) and neurodevelopmental disabilities (2, 3). Because postnatal treatment with systemic corticosteroids has been shown to improve pulmonary outcomes but worsen neurodevelopmental outcomes (4), Bassler and colleague...

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Veröffentlicht in:American journal of respiratory and critical care medicine 2019-07, Vol.200 (1), p.98-100
Hauptverfasser: Vazquez-Garcia, Gerardo A, Fierro, Julie L, Quinlan, Courtney M, Tapia, Ignacio E
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Sprache:eng
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Zusammenfassung:[...]this has been associated with increasing rates of bronchopulmonary dysplasia (BPD) and neurodevelopmental disabilities (2, 3). Because postnatal treatment with systemic corticosteroids has been shown to improve pulmonary outcomes but worsen neurodevelopmental outcomes (4), Bassler and colleagues tested inhaled budesonide as a preventive treatment for BPD and associated complications as part of the NEUROSIS (Neonatal European Study of Inhaled Steroids) trial group published in 2015 (5). Early (< 8 days) postnatal corticosteroids for preventing chronic lung disease in preterm infants. Forty-one neonates from three medical centers with birth weight
ISSN:1073-449X
1535-4970
DOI:10.1164/rccm.201808-1469RR