Reduction of serum albumin in non-critically ill patients during hospitalization is associated with incident hypoglycaemia

•Decreased albumin is associated with increased hypoglycaemia and mortality.•A direct correlation was found between decreased albumin and mean glucose levels.•The association between hypoglycaemia and mean glucose level is U-shaped. Our study looked at the association between changes in serum albumin (SA) levels during hospitalization and incidence of hypoglycaemia among non-critically ill patients. Included were patients discharged from internal medicine units with hospital stays ≤ 14 days. Patients were allocated to three groups: (1) admission SA > 3.5 g/dL with no decrease during hospitalization; (2) admission SA