Optos wide‐field imaging versus conventional camera imaging in Danish patients with type 2 diabetes

Purpose Diabetic retinopathy (DR) screening methods are costly, requiring specialized personnel and patient mydriasis. The Optos apparatus can be operated by nonspecialists and provides ultra‐wide‐field imaging, with 200° views of the retina in a single image. We compared DR grading obtained from Optos imaging with DR grading from conventional Topcon imaging. Methods We conducted a cross‐sectional study of 101 persons with diabetes who participated in the Addition‐DK 10‐year follow‐up study. Retina fundus photos using both Optos and Topcon imaging were taken for both eyes. All photos were graded by specialist ophthalmologic nurses, using a modified version of the ‘Proposed International Clinical DR severity scale’. We constructed frequency tables and assessed levels of agreement between Optos and Topcon gradings using weighted Kappa statistics, separately for peripheral and macular grading. We tested if the agreements between the two cameras were significantly different using a stratified Wilcoxon test. Results Significantly, more lesions in the periphery were identified by Optos compared with Topcon (p