Elevated plasma levels of soluble C-type lectin-like receptor 2 (CLEC2) in patients with thrombotic microangiopathy

Elevated plasma levels of soluble C-type lectin-like receptor 2 (CLEC2) in patients with thrombotic microangiopathy

Thrombotic microangiopathy (TMA) is caused by activated platelets. The plasma C-type lectin-like receptor 2 (CLEC2) levels in 58 patients with TMA were examined and compared with those in healthy volunteers and other diseases. The plasma levels of soluble platelet surface glycoprotein VI (GPVI) and...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Thrombosis research 2019-06, Vol.178, p.54-58
Hauptverfasser: Yamashita, Yoshiki, Suzuki, Kei, Mastumoto, Takeshi, Ikejiri, Makoto, Ohishi, Koji, Katayama, Naoyuki, Suzuki-Inoue, Katsue, Wada, Hideo
Format: Artikel
Sprache:eng
Schlagworte:
Adult
CLEC2
DIC
Female
Humans
Lectins, C-Type - blood
Male
Platelet activation
Thrombotic Microangiopathies - blood
Thrombotic Microangiopathies - diagnosis
Thrombotic Microangiopathies - pathology
TMA
Young Adult
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:Thrombotic microangiopathy (TMA) is caused by activated platelets. The plasma C-type lectin-like receptor 2 (CLEC2) levels in 58 patients with TMA were examined and compared with those in healthy volunteers and other diseases. The plasma levels of soluble platelet surface glycoprotein VI (GPVI) and CLEC2 were measured in patients with TMA. Plasma CLEC2 levels in patients with DIC and TMA were significantly higher (p 
ISSN:0049-3848
1879-2472
DOI:10.1016/j.thromres.2019.03.018