Preoperative C-reactive protein/albumin ratio predicts outcome of surgical papillary renal cell carcinoma

Preoperative C-reactive protein/albumin ratio predicts outcome of surgical papillary renal cell carcinoma

: To evaluate the prognostic values of some preoperative inflammation-based factors including C-reactive protein/albumin ratio (CRP/Alb) and platelet level in papillary renal cell carcinoma (PRCC). A total of 108 PRCC patients underwent partial or radical nephrectomy were retrospectively analyzed. T...

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Veröffentlicht in:Future oncology (London, England) England), 2019-05, Vol.15 (13), p.1459-1468
Hauptverfasser: Gao, Jie, Agizamhan, Sezim, Zhao, Xiaozhi, Jiang, Bo, Qin, Haixiang, Chen, Mengxia, Guo, Hongqian
Format: Artikel
Sprache:eng
Schlagworte:
Biomarkers
Blood platelets
Blood tests
C-reactive protein/albumin ratio
Colorectal cancer
Inflammation
Kidney cancer
Lymphocytes
Males
Medical prognosis
Metastasis
Neutrophils
papillary renal cell carcinoma
Patients
platelet level
Proteins
Statistical analysis
Surgery
survival
Survival analysis
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Zusammenfassung:: To evaluate the prognostic values of some preoperative inflammation-based factors including C-reactive protein/albumin ratio (CRP/Alb) and platelet level in papillary renal cell carcinoma (PRCC). A total of 108 PRCC patients underwent partial or radical nephrectomy were retrospectively analyzed. The prognostic values were determined with Kaplan–Meier analysis, univariate and multivariate COX regression models. CRP/Alb and platelet level were both significantly associated with subtype, Fuhrman grade, tumor stage, lymph node invasion, perinephric fat extension, shorter overall survival (OS) and disease-free survival (all p
ISSN:1479-6694
1744-8301
DOI:10.2217/fon-2018-0611