Correlation of Right Ventricular Wall Stress With Plasma B-Type Natriuretic Peptide Levels in Patients With Pulmonary Hypertension

Background: This study was designed to investigate the relationship between right ventricular wall stress (RVWS) and plasma B-type natriuretic peptide (BNP) levels in patients with pulmonary hypertension (PH). Methods and Results: The 57 consecutive PH patients and 8 control subjects were enrolled....

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Veröffentlicht in:	Circulation Journal 2019/05/24, Vol.83(6), pp.1278-1285
Hauptverfasser:	Uchiyama, Nami, Yuasa, Toshinori, Miyata, Masaaki, Horizoe, Yoshihisa, Chaen, Hideto, Kubota, Kayoko, Takasaki, Kunitsugu, Mizukami, Naoko, Kisanuki, Akira, Ohishi, Mitsuru
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged B-type natriuretic peptide Case-Control Studies Diastole Female Heart Ventricles - pathology Heart Ventricles - physiopathology Humans Hypertension, Pulmonary - blood Hypertension, Pulmonary - physiopathology Male Middle Aged Natriuretic Peptide, Brain - blood Pulmonary hypertension Right ventricular wall stress Stress, Mechanical Systole Ventricular Function, Right - physiology
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Zusammenfassung:	Background: This study was designed to investigate the relationship between right ventricular wall stress (RVWS) and plasma B-type natriuretic peptide (BNP) levels in patients with pulmonary hypertension (PH). Methods and Results: The 57 consecutive PH patients and 8 control subjects were enrolled. Right heart catheterization (RHC), echocardiography, and BNP measurements were performed, and RVWS and left ventricular wall stress (LVWS) were calculated with the formula based on Laplace’s law. Systolic RVWS and end-diastolic RVWS were higher in PH patients compared with controls (systolic RVWS: 77±41 vs. 17±5 kdynes/cm2(P
ISSN:	1346-9843 1347-4820 1347-4820
DOI:	10.1253/circj.CJ-18-1155