Prevention of α-crystallin glycation and aggregation using l-lysine results in the inhibition of in vitro catalase heat-induced-aggregation and suppression of cataract formation in the diabetic rat

The principle role of α-crystallin is chaperoning activity that protect s other proteins against different stresses. High glucose concentration induces the osmotic stress and results in biomacromolecules glycation, which is subsequently cause their conformational and functional changes. Here, the ro...

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Veröffentlicht in:	International journal of biological macromolecules 2019-07, Vol.132, p.1200-1207
Hauptverfasser:	Bahmani, Fereshteh, Bathaie, S. Zahra, Aldavood, S. Javid, Ghahghaei, Arezou
Format:	Artikel
Sprache:	eng
Schlagworte:	Activity AGEs Antioxidant Chaperone Enzyme Glycation Structure
Online-Zugang:	Volltext
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