Association of antioxidants and vitamin D level with inflammation in children with atopic dermatitis

Background Changing the resources of vitamin D and antioxidant nutrients may affect the course of allergic diseases. The aim of the study was to investigate the association between CoQ10, vitamin D, retinol, and α‐tocopherol serum levels and severity of atopic dermatitis (AD) in children. Methods Twenty‐nine children with AD aged from 1 to 15 years were enrolled into the study. The severity of AD was categorized into mild or moderate (≤50 points in SCORAD – Scoring Atopic Dermatitis index) and severe (>50 SCORAD points). The control group was comprised of 22 children with negative history of allergy aged from 2 to 15. The serum measurements included vitamin D, retinol, α‐tocopherol, CoQ10, C‐reactive protein (CRP), complete blood count (CBC), and total immunoglobulin E (IgE). Results Low vitamin D concentration (