INHBA gene silencing inhibits gastric cancer cell migration and invasion by impeding activation of the TGF‐β signaling pathway

Gastric cancer (GC) is the fourth largest cancer in the world, with a 5‐year survival rate of

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Bibliographische Detailangaben
Veröffentlicht in:	Journal of cellular physiology 2019-10, Vol.234 (10), p.18065-18074
Hauptverfasser:	Chen, Zong‐Lin, Qin, Lu, Peng, Xu‐Bin, Hu, Yu, Liu, Bo
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Aged Animals Cancer Cell adhesion & migration Cell Line, Tumor Cell migration Cell Movement Cell Proliferation Female Gastric cancer Gene expression Gene Expression Regulation, Neoplastic Gene silencing Genes Growth factors Humans INHBA gene Inhibin inhibin βA Inhibin-beta Subunits - genetics Inhibin-beta Subunits - metabolism invasion Kinases Male Mice, Nude Middle Aged migration Neoplasm Invasiveness RNA Interference RNAi Therapeutics Signal Transduction Signaling Stomach Neoplasms - genetics Stomach Neoplasms - metabolism Stomach Neoplasms - pathology Stomach Neoplasms - therapy Survival TGF‐β signaling pathway Transforming growth factor Transforming Growth Factor beta - genetics Transforming Growth Factor beta - metabolism Transforming growth factor-b Tumor Burden Tumors Xenograft Model Antitumor Assays Xenografts Xenotransplantation Young Adult
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Beschreibung
Zusammenfassung:	Gastric cancer (GC) is the fourth largest cancer in the world, with a 5‐year survival rate of
ISSN:	0021-9541 1097-4652
DOI:	10.1002/jcp.28439