Multifunctional two dimensional Bi2Se3 nanodiscs for combined antibacterial and anti-inflammatory therapy for bacterial infections

A multifunctional platform based on two-dimensional nanomaterials for combined antibacterial and anti-inflammatory therapy is developed. Bi2Se3 nanodiscs selectively eradicate Gram-positive bacteria with a low risk of drug resistance. Moreover, Bi2Se3 nanodiscs with antioxidant activity relieve intr...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Chemical communications (Cambridge, England) England), 2019, Vol.55 (33), p.4877-4880
Hauptverfasser:	Ouyang, Jiang, Wen, Mei, Chen, Wansong, Tan, Yanni, Liu, Zhenjun, Xu, Qunfang, Zeng, Ke, Deng, Liu, You-Nian Liu
Format:	Artikel
Sprache:	eng
Schlagworte:	Antiinfectives and antibacterials Antioxidants Bacteria Bacterial infections Drug resistance Gram-positive bacteria Macrophages Nanomaterials Oxidation resistance Therapy
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	A multifunctional platform based on two-dimensional nanomaterials for combined antibacterial and anti-inflammatory therapy is developed. Bi2Se3 nanodiscs selectively eradicate Gram-positive bacteria with a low risk of drug resistance. Moreover, Bi2Se3 nanodiscs with antioxidant activity relieve intracellular oxidative stress of macrophages to suppress inflammation caused by bacterial infections.
ISSN:	1359-7345 1364-548X
DOI:	10.1039/c9cc01129c