Cu-Catalyzed atom transfer radical addition reactions of alkenes with α-bromoacetonitrile

A practical, simple, and efficient copper-catalyzed atom transfer radical addition reaction of alkenes with α-bromoacetonitrile is realized. With this methodology, various γ-bromonitriles and β,γ-unsaturated nitriles were efficiently constructed. A novel copper-catalyzed ATRA reaction of alkenes with α-bromoacetonitrile for the synthesis of γ-bromonitriles and β,γ-unsaturated nitriles was developed.