Prognostic impact of circulating tumor DNA status post–allogeneic hematopoietic stem cell transplantation in AML and MDS

This study was performed to assess the utility of tumor-derived fragmentary DNA, or circulating tumor DNA (ctDNA), for identifying high-risk patients for relapse of acute myeloid leukemia and myelodysplastic syndrome (AML/MDS) after undergoing myeloablative allogeneic hematopoietic stem cell transpl...

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Veröffentlicht in:	Blood 2019-06, Vol.133 (25), p.2682-2695
Hauptverfasser:	Nakamura, Sousuke, Yokoyama, Kazuaki, Shimizu, Eigo, Yusa, Nozomi, Kondoh, Kanya, Ogawa, Miho, Takei, Tomomi, Kobayashi, Asako, Ito, Mika, Isobe, Masamichi, Konuma, Takaaki, Kato, Seiko, Kasajima, Rika, Wada, Yuka, Nagamura-Inoue, Tokiko, Yamaguchi, Rui, Takahashi, Satoshi, Imoto, Seiya, Miyano, Satoru, Tojo, Arinobu
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Aged Biomarkers, Tumor - blood Circulating Tumor DNA - analysis Female Hematopoietic Stem Cell Transplantation - mortality Humans Leukemia, Myeloid, Acute - blood Leukemia, Myeloid, Acute - genetics Leukemia, Myeloid, Acute - therapy Male Middle Aged Myelodysplastic Syndromes - blood Myelodysplastic Syndromes - genetics Myelodysplastic Syndromes - therapy Neoplasm Recurrence, Local - blood Neoplasm Recurrence, Local - genetics Neoplasm Recurrence, Local - mortality Prognosis Retrospective Studies Survival Analysis Young Adult
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