Ticagrelor Versus Clopidogrel in Patients With STEMI Treated With Fibrinolysis: TREAT Trial

The efficacy of ticagrelor in the long-term post-ST-segment elevation myocardial infarction (STEMI) treated with fibrinolytic therapy remains uncertain. The purpose of this study was to evaluate the efficacy of ticagrelor when compared with clopidogrel in STEMI patients treated with fibrinolytic the...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Journal of the American College of Cardiology 2019-06, Vol.73 (22), p.2819-2828
Hauptverfasser:	Berwanger, Otavio, Lopes, Renato D, Moia, Diogo D F, Fonseca, Francisco A, Jiang, Lixin, Goodman, Shaun G, Nicholls, Stephen J, Parkhomenko, Alexander, Averkov, Oleg, Tajer, Carlos, Malaga, Germán, Saraiva, Jose F K, Guimaraes, Helio P, de Barros E Silva, Pedro G M, Damiani, Lucas P, Santos, Renato H N, Paisani, Denise M, Miranda, Tamiris A, Valeis, Nanci, Piegas, Leopoldo S, Granger, Christopher B, White, Harvey D, Nicolau, Jose C
Format:	Artikel
Sprache:	eng
Schlagworte:	Adjudication Aged Bleeding Cardiology Cardiovascular diseases Cause of Death Cerebral infarction Clopidogrel Clopidogrel - adverse effects Clopidogrel - therapeutic use Confidence intervals Dose-Response Relationship, Drug Drug Administration Schedule Drug therapy Electrocardiography Female Fibrin Fibrinolysis Heart attacks Humans Ischemia Long-Term Care Male Middle Aged Mortality Myocardial infarction Patients Pharmacology Randomization ST Elevation Myocardial Infarction - drug therapy ST Elevation Myocardial Infarction - mortality Statistical analysis Stroke Studies Survival Analysis Therapy Thrombolysis Thrombolytic Therapy - methods Ticagrelor - adverse effects Ticagrelor - therapeutic use Transient ischemic attack Treatment Outcome
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	The efficacy of ticagrelor in the long-term post-ST-segment elevation myocardial infarction (STEMI) treated with fibrinolytic therapy remains uncertain. The purpose of this study was to evaluate the efficacy of ticagrelor when compared with clopidogrel in STEMI patients treated with fibrinolytic therapy. This international, multicenter, randomized, open-label with blinded endpoint adjudication trial enrolled 3,799 patients (age
ISSN:	0735-1097 1558-3597
DOI:	10.1016/j.jacc.2019.03.011