Transcatheter Aortic-Valve Replacement with a Balloon-Expandable Valve in Low-Risk Patients

Transcatheter Aortic-Valve Replacement with a Balloon-Expandable Valve in Low-Risk Patients

In a randomized trial, 1000 patients with severe aortic stenosis who were at low risk for death with surgery were assigned to undergo transcatheter aortic-valve replacement with a balloon-expandable valve or surgical aortic-valve replacement. At 1 year, the rate of death, stroke, or rehospitalizatio...

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Veröffentlicht in:The New England journal of medicine 2019-05, Vol.380 (18), p.1695-1705
Hauptverfasser: Mack, Michael J, Leon, Martin B, Thourani, Vinod H, Makkar, Raj, Kodali, Susheel K, Russo, Mark, Kapadia, Samir R, Malaisrie, S. Chris, Cohen, David J, Pibarot, Philippe, Leipsic, Jonathon, Hahn, Rebecca T, Blanke, Philipp, Williams, Mathew R, McCabe, James M, Brown, David L, Babaliaros, Vasilis, Goldman, Scott, Szeto, Wilson Y, Genereux, Philippe, Pershad, Ashish, Pocock, Stuart J, Alu, Maria C, Webb, John G, Smith, Craig R
Format: Artikel
Sprache:eng
Schlagworte:
Aged
Aortic stenosis
Aortic Valve - surgery
Aortic Valve Stenosis - complications
Aortic Valve Stenosis - mortality
Aortic Valve Stenosis - surgery
Atrial Fibrillation - etiology
Cardiomyopathy
Catheters
Death
Female
Fibrillation
Heart surgery
Heart Valve Prosthesis
Heart Valve Prosthesis Implantation - adverse effects
Heart Valve Prosthesis Implantation - methods
Humans
Kaplan-Meier Estimate
Length of Stay
Male
Patient Readmission - statistics & numerical data
Patients
Postoperative Complications - epidemiology
Prosthesis Design
Regurgitation
Risk Factors
Stenosis
Stroke
Stroke - epidemiology
Stroke - etiology
Surgery
Surgical outcomes
Thorax
Transcatheter Aortic Valve Replacement - adverse effects
Transcatheter Aortic Valve Replacement - instrumentation
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Beschreibung
Zusammenfassung:In a randomized trial, 1000 patients with severe aortic stenosis who were at low risk for death with surgery were assigned to undergo transcatheter aortic-valve replacement with a balloon-expandable valve or surgical aortic-valve replacement. At 1 year, the rate of death, stroke, or rehospitalization was significantly lower in the TAVR group.
ISSN:0028-4793
1533-4406
DOI:10.1056/NEJMoa1814052