A Comparative Study Evaluating the Incidence of Colorectal Neoplasia(s) in Candidates for Bariatric Surgery by Screening Colonoscopy, 40–49 Versus 50–65 Years Old: a Preliminary Study

Introduction Obesity and metabolic syndrome (MetS) are associated with colorectal neoplasia (CRN) and carcinoma (CRC). Whether such subjects must undergo screening colonoscopy (SC) earlier, is unknown. Incidences of CRNs in 40–49- versus 50–65-year-old bariatric patients were compared by SC. No pros...

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Veröffentlicht in:Obesity surgery 2019-08, Vol.29 (8), p.2430-2435
Hauptverfasser: Toydemir, Toygar, Özgen, Görkem, Çalıkoğlu, İsmail, Ersoy, Özdal, Yerdel, Mehmet Ali
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Sprache:eng
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Zusammenfassung:Introduction Obesity and metabolic syndrome (MetS) are associated with colorectal neoplasia (CRN) and carcinoma (CRC). Whether such subjects must undergo screening colonoscopy (SC) earlier, is unknown. Incidences of CRNs in 40–49- versus 50–65-year-old bariatric patients were compared by SC. No prospective data on SC is available in morbidly obese/MetS. Material and Methods Surgical weight loss candidates over 39 years of age, asymptomatic, and average-risk for CRC offered SC. Those giving written informed consent were enrolled. Colonoscopies were done by the same surgeon. Smoking/drinking history, fasting blood glucose (FBG), insulin, C-peptide, triglyceride, high density lipoprotein, vitamin D, HbA1c, and insulin resistance parameters were recorded. CRN rate and the distribution of variables in patients 40–49 years of age were compared with 50–65. Student’s t and Chi-square tests were used as appropriate. P  
ISSN:0960-8923
1708-0428
DOI:10.1007/s11695-019-03819-2