Dietary trans and saturated fatty acids effects on semen quality, hormonal levels and expression of genes related to steroid metabolism in mouse adipose tissue

Our objectives were to assess sperm alteration and adipose tissue (AT) genes expression related to steroid metabolism subsequent to fatty acids consumption. Twenty‐nine mature male mice were divided into: fat diet (FD; n = 15) and the control group (n = 14). FD group was fed with low level of trans...

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Veröffentlicht in:	Andrologia 2019-06, Vol.51 (5), p.e13259-n/a
Hauptverfasser:	Molaie, Solmaz, Shahverdi, Abdolhossein, Sharafi, Mohsen, Shahhoseini, Maryam, Rashki Ghaleno, Leila, Esmaeili, Vahid, Abed‐Heydari, Elham, Numan Bucak, Mustafa, Alizadeh, AliReza
Format:	Artikel
Sprache:	eng
Schlagworte:	17β-Estradiol Adipose tissue Adipose Tissue - metabolism Androgens - blood Androgens - metabolism Animals Diet, High-Fat - adverse effects Dietary Fats - adverse effects dietary fatty acids Estrogens - blood Estrogens - metabolism Fatty acids Fatty Acids - adverse effects Male Metabolism Mice Models, Animal mRNA Semen semen quality Sperm Sperm Count steroidogenic enzyme gene expression Steroids - metabolism Testosterone
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Zusammenfassung:	Our objectives were to assess sperm alteration and adipose tissue (AT) genes expression related to steroid metabolism subsequent to fatty acids consumption. Twenty‐nine mature male mice were divided into: fat diet (FD; n = 15) and the control group (n = 14). FD group was fed with low level of trans and saturated fatty acids source for 60 days. Sperm parameters, levels of hormones and the mRNA abundance of the target genes in AT were assessed. The sperm concentration, total and progressive motilities were lower in FD group compared to that of control (p
ISSN:	0303-4569 1439-0272
DOI:	10.1111/and.13259