Comparison of initial treatment with and without corticosteroids for suspected acute pancreatitis in dogs

Objectives To compare initial treatment with and without corticosteroids for acute pancreatitis in dogs and investigate the therapeutic efficacy and prognosis. Materials and Methods Sixty‐five dogs were included in this non‐blinded, non‐randomised clinical study. Dogs with acute pancreatitis receive...

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Veröffentlicht in:Journal of small animal practice 2019-05, Vol.60 (5), p.298-304
Hauptverfasser: Okanishi, H., Nagata, T., Nakane, S., Watari, T.
Format: Artikel
Sprache:eng
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Zusammenfassung:Objectives To compare initial treatment with and without corticosteroids for acute pancreatitis in dogs and investigate the therapeutic efficacy and prognosis. Materials and Methods Sixty‐five dogs were included in this non‐blinded, non‐randomised clinical study. Dogs with acute pancreatitis received treatment either with dose of 1 mg/kg/day prednisolone (n=45) or without prednisolone (n=20). Response to treatment was based on changes in the C‐reactive protein concentration, improvement in clinical signs, duration of hospitalisation, mortality and recurrence rate. Results From the third day of hospitalisation, C‐reactive protein concentration was significantly lower in the prednisolone group than that in the non‐prednisolone group. The number of days required to reach a C‐reactive protein concentration of
ISSN:0022-4510
1748-5827
DOI:10.1111/jsap.12994