Successful Treatment of Antibiotic-resistant, Poly-microbial Bone Infection With Bacteriophages and Antibiotics Combination

Successful Treatment of Antibiotic-resistant, Poly-microbial Bone Infection With Bacteriophages and Antibiotics Combination

A patient with a trauma-related left tibial infection associated with extensively drug-resistant Acinetobacter baumannii and multidrug-resistant Klebsiella pneumoniae was treated with bacteriophages and antibiotics. There was rapid tissue healing and positive culture eradication. As a result, the pa...

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Veröffentlicht in:Clinical infectious diseases 2019-11, Vol.69 (11), p.2015-2018
Hauptverfasser: Nir-Paz, Ran, Gelman, Daniel, Khouri, Ayman, Sisson, Brittany M., Fackler, Joseph, Alkalay-Oren, Sivan, Khalifa, Leron, Rimon, Amit, Yerushalmy, Ortal, Bader, Reem, Amit, Sharon, Coppenhagen-Glazer, Shunit, Henry, Matthew, Quinones, Javier, Malagon, Francisco, Biswas, Biswajit, Moses, Allon E., Merril, Greg, Schooley, Robert T., Brownstein, Michael J., Weil, Yoram A., Hazan, Ronen
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Sprache:eng
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Zusammenfassung:A patient with a trauma-related left tibial infection associated with extensively drug-resistant Acinetobacter baumannii and multidrug-resistant Klebsiella pneumoniae was treated with bacteriophages and antibiotics. There was rapid tissue healing and positive culture eradication. As a result, the patient’s leg did not have to be amputated and he is undergoing rehabilitation.
ISSN:1058-4838
1537-6591
DOI:10.1093/cid/ciz222