Task-related functional connectivity of anterior cingutate in opiate drug addicts during physical detoxification: a task fMRI study

To explore the brain areas which have abnormal functional connectivity with anterior cingutate in opiate drug dependence during physical detoxification using a task-related functional magnetic resonance imaging(fMRI), and to find out the role of anterior cingutate dysfunction in the relapse of opiat...

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Veröffentlicht in:Zhong hua yi xue za zhi 2019-03, Vol.99 (9), p.700-703
Hauptverfasser: Han, Y, Sun, T, Zheng, X L, Jiang, Z Q, Lou, F Y, Zhang, S J
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Sprache:chi
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Zusammenfassung:To explore the brain areas which have abnormal functional connectivity with anterior cingutate in opiate drug dependence during physical detoxification using a task-related functional magnetic resonance imaging(fMRI), and to find out the role of anterior cingutate dysfunction in the relapse of opiate drug addicts during physical detoxification. From January to December 2016, eighteen participants of opiate drug addicts during physical detoxification who completed in Drug Rehabilitation Center of Anhui Province, and eighteen healthy controls recruited performed a cue-elicited craving task in a MRI scanner while signal data were collected. Two regions of interest were the right anterior cingutate and the left anterior cingutate, then the linear correlation between the whole brain and the anterior cingutates was calculated to find out the abnormal functional connectivity of the anterior cingutates. Contrasted experimental group with the healthy controls, the functional connectivity of bilateral fusiform gyrus, c
ISSN:0376-2491
DOI:10.3760/cma.j.issn.0376-2491.2019.09.013