Tumor-educated platelets

Liquid biopsies have been considered the holy grail in achieving effective cancer management, with blood tests offering a minimally invasive, safe, and sensitive alternative or complementary approach for tissue biopsies. Currently, blood-based liquid biopsy measurements focus on the evaluation of bi...

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Veröffentlicht in:Blood 2019-05, Vol.133 (22), p.2359-2364
Hauptverfasser: In ‘t Veld, Sjors G.J.G., Wurdinger, Thomas
Format: Artikel
Sprache:eng
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Zusammenfassung:Liquid biopsies have been considered the holy grail in achieving effective cancer management, with blood tests offering a minimally invasive, safe, and sensitive alternative or complementary approach for tissue biopsies. Currently, blood-based liquid biopsy measurements focus on the evaluation of biomarker types, including circulating tumor DNA, circulating tumor cells, extracellular vesicles (exosomes and oncosomes), and tumor-educated platelets (TEPs). Despite the potential of individual techniques, each has its own advantages and disadvantages. Here, we provide further insight into TEPs. [Display omitted]
ISSN:0006-4971
1528-0020
DOI:10.1182/blood-2018-12-852830