Real‐life experience in the treatment of solar urticaria: retrospective cohort study

Summary Background Solar urticaria (SU) is a rare photodermatosis causing a significant impact on patients' quality of life (QoL), and treatment is often challenging. Aim To analyse clinical experience with a tailored stepwise therapeutic approach. Methods A retrospective cohort design was used...

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Veröffentlicht in:Clinical and experimental dermatology 2019-07, Vol.44 (5), p.e164-e170
Hauptverfasser: Snast, I., Lapidoth, M., Uvaidov, V., Enk, C. D., Mazor, S., Hodak, E., Levi, A.
Format: Artikel
Sprache:eng
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Zusammenfassung:Summary Background Solar urticaria (SU) is a rare photodermatosis causing a significant impact on patients' quality of life (QoL), and treatment is often challenging. Aim To analyse clinical experience with a tailored stepwise therapeutic approach. Methods A retrospective cohort design was used. Patients with suspected SU underwent laboratory investigations and photoprovocation. Those with a high minimal urticaria dose (MUD) were treated with a single antihistamine (protocol 1), and those with a lower MUD received three types of antihistamines (protocol 2); both protocols included a leucotriene receptor antagonist (LRA). In cases of failure, treatment was switched to omalizumab at doses of
ISSN:0307-6938
1365-2230
DOI:10.1111/ced.13960