Flow Mediated Skin Fluorescence technique reveals remarkable effect of age on microcirculation and metabolic regulation in type 1 diabetes

Flow Mediated Skin Fluorescence technique reveals remarkable effect of age on microcirculation and metabolic regulation in type 1 diabetes

Flow Mediated Skin Fluorescence (FMSF) is a novel technique for non-invasive evaluation of the microcirculation and metabolic regulation. This study describes the diagnostic potential of FMSF for type 1 diabetes (DM1). All study participants, in both the control (n = 31) and DM1 (n = 40) groups, wer...

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Veröffentlicht in:Microvascular research 2019-07, Vol.124, p.19-24
Hauptverfasser: Katarzynska, Joanna, Borkowska, Anna, Czajkowski, Przemyslaw, Los, Agnieszka, Szczerbinski, Lukasz, Milewska-Kranc, Agnieszka, Marcinek, Andrzej, Kretowski, Adam, Cypryk, Katarzyna, Gebicki, Jerzy
Format: Artikel
Sprache:eng
Schlagworte:
FMSF technique
Metabolic regulation
Microcirculation
NADH fluorescence
Type 1 diabetes
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Zusammenfassung:Flow Mediated Skin Fluorescence (FMSF) is a novel technique for non-invasive evaluation of the microcirculation and metabolic regulation. This study describes the diagnostic potential of FMSF for type 1 diabetes (DM1). All study participants, in both the control (n = 31) and DM1 (n = 40) groups, were between the ages of 30–49 y. The patients in the DM1 group had all been suffering from diabetes for at least 10 y. The parameters HRindex, HRmax and MR inversely correlate with age and BMI. An unidentified compensatory effect was observed among the younger members of the DM1 group. The majority of DM1 patients with HRindex 
ISSN:0026-2862
1095-9319
DOI:10.1016/j.mvr.2019.02.005