Binding varicella zoster virus: an underestimated facet of insulin-degrading enzyme´s implication for Alzheimer´s disease pathology?

Binding varicella zoster virus: an underestimated facet of insulin-degrading enzyme´s implication for Alzheimer´s disease pathology?

We shortly discuss a possible contribution of insulin-degrading enzyme to Alzheimer´s disease pathology by binding varicella zoster virus glycoprotein E, which increases the infectivity and cell–cell spread of the virus.

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Bibliographische Detailangaben
Veröffentlicht in:European archives of psychiatry and clinical neuroscience 2020-06, Vol.270 (4), p.495-496
Hauptverfasser: Bernstein, Hans-Gert, Keilhoff, Gerburg, Dobrowolny, Henrik, Steiner, Johann
Format: Artikel
Sprache:eng
Schlagworte:
Alzheimer's disease
Chicken pox
Enzymes
Glycoprotein E
Infectivity
Insulin
Insulysin
Letter to the Editor
Medicine
Medicine & Public Health
Neurosciences
Psychiatry
Varicella
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Beschreibung
Zusammenfassung:We shortly discuss a possible contribution of insulin-degrading enzyme to Alzheimer´s disease pathology by binding varicella zoster virus glycoprotein E, which increases the infectivity and cell–cell spread of the virus.
ISSN:0940-1334
1433-8491
DOI:10.1007/s00406-019-00995-1