Clinical mid- to long-term outcome after autologous chondrocyte implantation for patellar cartilage lesions and its correlation with the geometry of the femoral trochlea

The aim was to investigate the clinical results after autologous chondrocyte implantation (ACI) at the patella in a mid- to long-term course, and whether trochlear dysplasia has an influence on the outcome. Inclusion criteria were ACI for focal patella cartilage defects and preoperative magnetic resonance imaging (MRI). Patients with previous trochleoplasty or osteotomy have been excluded. Trochlea morphology was evaluated by sulcus depth, sulcus angle, lateral condyle index (LCI) and Dejour's classification for trochlea dysplasia. The clinical outcome was evaluated by a questionnaire including the Kujala- and IKDC-Scores. Survival of the ACI was analysed by the Kaplan–Meier method. A correlation analysis between morphologic parameters and clinical scores was performed. Seventy-eight patients (mean age 33.2 ± 10.7 years) were included (mean follow-up 6.5 ± 3.4 years). The mean sulcus depth was 5.0 ± 1.6 mm (normal value ≥5 mm), the mean sulcus angle was 153.4 ± 9.0° (normal value ≤145°) and the mean LCI was 84.9 ± 7.5% (normal value ≥90%). Major trochlea dysplasia (grades B–D) was seen in 29 patients (36.7%). Five-year survival rate was 98%, satisfaction-rate was 78.9% and the mean clinical scores were 67.6 ± 20.2 for the Kujala-Score and 64.7 ± 20.2 for the IKDC-Score. A lower LCI showed significant correlation with a lower IKDC score (r = 0.25; p = 0.037). The present study reports an excellent survival rate and a good satisfaction rate in a mid- to long-term course after patella ACI. The clinical scores show a high variance and there is evidence that a pathologic trochlea correlates with inferior results.