A sensitive photoelectrochemical assay of miRNA-155 based on a CdSe QDs//NPC-ZnO polyhedra photocurrent-direction switching system and target-triggered strand displacement amplification strategy

A sensitive photoelectrochemical assay of miRNA-155 based on a CdSe QDs//NPC-ZnO polyhedra photocurrent-direction switching system and target-triggered strand displacement amplification strategy

Herein, a new photoelectrochemical (PEC) biosensor based on a photocurrent direction switching system and target-triggered strand displacement amplification strategy was developed for the sensitive detection of microRNA (miRNA)-155, and it showed excellent selectivity and a low detection limit of ab...

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Veröffentlicht in:Chemical communications (Cambridge, England) England), 2019-02, Vol.55 (15), p.2182-2185
Hauptverfasser: Meng, Leixia, Li, Yanmei, Yang, Ruiying, Zhang, Xiaohua, Du, Cuicui, Chen, Jinhua
Format: Artikel
Sprache:eng
Schlagworte:
Amplification
Biosensors
Deoxyribonucleic acid
DNA
Gene sequencing
Photoelectric effect
Photoelectric emission
Ribonucleic acid
RNA
Selectivity
Switching
Zinc oxide
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Zusammenfassung:Herein, a new photoelectrochemical (PEC) biosensor based on a photocurrent direction switching system and target-triggered strand displacement amplification strategy was developed for the sensitive detection of microRNA (miRNA)-155, and it showed excellent selectivity and a low detection limit of about 49 aM.
ISSN:1359-7345
1364-548X
DOI:10.1039/c8cc09411j