Macroalgae to nanoparticles: Study of Ulva lactuca L. role in biosynthesis of gold and silver nanoparticles and of their cytotoxicity on colon cancer cell lines
Marine bio-resources are being widely studied as an invaluable source of compounds with therapeutic applicability. In particular, macroalgae contain an extended variety of bioactive compounds with different structures and promising biological applications. In this work, Ulva lactuca L. (hereafter UL...
Gespeichert in:
| Veröffentlicht in: | Materials Science & Engineering C 2019-04, Vol.97, p.498-509 |
|---|---|
| Hauptverfasser: | , , , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 509 |
|---|---|
| container_issue | |
| container_start_page | 498 |
| container_title | Materials Science & Engineering C |
| container_volume | 97 |
| creator | González-Ballesteros, Noelia Rodríguez-Argüelles, M. Carmen Prado-López, Sonia Lastra, Mariano Grimaldi, Maria Cavazza, Antonella Nasi, Lucia Salviati, Giancarlo Bigi, Franca |
| description | Marine bio-resources are being widely studied as an invaluable source of compounds with therapeutic applicability. In particular, macroalgae contain an extended variety of bioactive compounds with different structures and promising biological applications. In this work, Ulva lactuca L. (hereafter UL) was utilyzed for the synthesis of gold and silver nanoparticles. Full characterization by UV–Vis spectroscopy, TEM, HRTEM and STEM miscroscopies, Z Potential and FTIR spectroscopy was performed. The first time in the scientific literature, the composition of carbohydrates of UL extract and their changes observed after nanoparticles synthesis were explored in order to investigate their possible role in the biosynthetic process. The reducing power, total phenolic content and DPPH scavenging activity of UL extract, Au@UL and Ag@UL nanoparticles were determined. The effects of UL extract, Au@UL and Ag@UL were tested in vitro on the colon cancer cell lines HT-29 and Caco-2, on normal primary neonatal dermal fibroblast cell line PCS-201-010, as well as on normal colon cell line CCD-112CoN. Lastly, the apoptotic activity and cellular uptake evaluation was determined for Au@UL and Ag@UL.
•Aqueous extract of Ulva lactuca served to synthesize gold and silver nanoparticles.•The composition of the extract before and after the synthesis was determined.•This provided new information about the possible role of sugars during the synthesis.•The effects of UL extract, Au@UL and Ag@UL were tested in vitro on colon cancer cells.•Apoptotic activity and cellular uptake evaluation was determined for Au@UL and Ag@UL. |
| doi_str_mv | 10.1016/j.msec.2018.12.066 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_2179455773</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>S0928493118326729</els_id><sourcerecordid>2179455773</sourcerecordid><originalsourceid>FETCH-LOGICAL-c421t-4373ebd7738f23101c6b87f377bbfdc71bf14bb53f2fd687ad9e0179a5ec8e993</originalsourceid><addsrcrecordid>eNp9kTuP1DAUhS0EYoeFP0CBLNHQJPiRxAmiWa14SYMoYGvLj5vFI4892M6I-Tf8VBxmQYKCxrfwd869Ogehp5S0lNDh5a7dZzAtI3RsKWvJMNxDGzoK3hA60ftoQyY2Nt3E6QV6lPOOkGHkgj1EF5wMYpy42KAfH5VJUflbBbhEHFSIB5WKMx7yK_y5LPaE44xv_FFhr0xZjMLbFqfoAbuAtYv5FMpXyC6v3G30FqtgcXb-COlvv18fFaq4S9icSizxuzOu1BUBm-jXVwVTdQa8x94FyI_Rg1n5DE_u5iW6efvmy_X7Zvvp3Yfrq21jOkZL03HBQVsh-DgzXuMxgx7FzIXQerZGUD3TTuuez2y2wyiUnYBQMakezAjTxC_Ri7PvIcVvC-Qi9y6vZ6gAccmSVbjr-7qgos__QXdxSaFeV6madk-6nlWKnamab84JZnlIbq_SSVIi1_7kTq79ybU_SZms_VXRszvrRe_B_pH8LqwCr88A1CyODpLMxkHNzLoEpkgb3f_8fwLIiq6K</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2193150452</pqid></control><display><type>article</type><title>Macroalgae to nanoparticles: Study of Ulva lactuca L. role in biosynthesis of gold and silver nanoparticles and of their cytotoxicity on colon cancer cell lines</title><source>MEDLINE</source><source>Elsevier ScienceDirect Journals</source><creator>González-Ballesteros, Noelia ; Rodríguez-Argüelles, M. Carmen ; Prado-López, Sonia ; Lastra, Mariano ; Grimaldi, Maria ; Cavazza, Antonella ; Nasi, Lucia ; Salviati, Giancarlo ; Bigi, Franca</creator><creatorcontrib>González-Ballesteros, Noelia ; Rodríguez-Argüelles, M. Carmen ; Prado-López, Sonia ; Lastra, Mariano ; Grimaldi, Maria ; Cavazza, Antonella ; Nasi, Lucia ; Salviati, Giancarlo ; Bigi, Franca</creatorcontrib><description>Marine bio-resources are being widely studied as an invaluable source of compounds with therapeutic applicability. In particular, macroalgae contain an extended variety of bioactive compounds with different structures and promising biological applications. In this work, Ulva lactuca L. (hereafter UL) was utilyzed for the synthesis of gold and silver nanoparticles. Full characterization by UV–Vis spectroscopy, TEM, HRTEM and STEM miscroscopies, Z Potential and FTIR spectroscopy was performed. The first time in the scientific literature, the composition of carbohydrates of UL extract and their changes observed after nanoparticles synthesis were explored in order to investigate their possible role in the biosynthetic process. The reducing power, total phenolic content and DPPH scavenging activity of UL extract, Au@UL and Ag@UL nanoparticles were determined. The effects of UL extract, Au@UL and Ag@UL were tested in vitro on the colon cancer cell lines HT-29 and Caco-2, on normal primary neonatal dermal fibroblast cell line PCS-201-010, as well as on normal colon cell line CCD-112CoN. Lastly, the apoptotic activity and cellular uptake evaluation was determined for Au@UL and Ag@UL.
•Aqueous extract of Ulva lactuca served to synthesize gold and silver nanoparticles.•The composition of the extract before and after the synthesis was determined.•This provided new information about the possible role of sugars during the synthesis.•The effects of UL extract, Au@UL and Ag@UL were tested in vitro on colon cancer cells.•Apoptotic activity and cellular uptake evaluation was determined for Au@UL and Ag@UL.</description><identifier>ISSN: 0928-4931</identifier><identifier>EISSN: 1873-0191</identifier><identifier>DOI: 10.1016/j.msec.2018.12.066</identifier><identifier>PMID: 30678937</identifier><language>eng</language><publisher>Netherlands: Elsevier B.V</publisher><subject>AgNP ; Algae ; Antioxidants - chemistry ; Apoptosis ; Apoptosis - drug effects ; AuNP ; Bioactive compounds ; Biocompatibility ; Biosynthesis ; Biotechnology ; Caco-2 ; Cancer ; Carbohydrates ; Carbohydrates - analysis ; Carbohydrates - chemistry ; Cell Line, Tumor ; Cell Proliferation - drug effects ; Chemical compounds ; Colon ; Colon cancer ; Colonic Neoplasms - metabolism ; Colonic Neoplasms - pathology ; Colorectal cancer ; Cytotoxicity ; Fourier transforms ; Gold ; Gold - chemistry ; HT-29 ; Humans ; Marine resources ; Materials science ; Metal Nanoparticles - chemistry ; Metal Nanoparticles - toxicity ; Microscopy, Electron, Transmission ; Nanoparticles ; Neonates ; Pharmacology ; Phenolic compounds ; Phenols ; Phenols - chemistry ; Plant Extracts - chemistry ; Scavenging ; Seaweeds ; Silver ; Silver - chemistry ; Skin ; Spectrophotometry ; Spectroscopy ; Spectroscopy, Fourier Transform Infrared ; Spectrum analysis ; Toxicity ; Tumor cell lines ; Ulva - metabolism ; Ulva lactuca</subject><ispartof>Materials Science & Engineering C, 2019-04, Vol.97, p.498-509</ispartof><rights>2018 Elsevier B.V.</rights><rights>Copyright © 2018 Elsevier B.V. All rights reserved.</rights><rights>Copyright Elsevier BV Apr 2019</rights><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c421t-4373ebd7738f23101c6b87f377bbfdc71bf14bb53f2fd687ad9e0179a5ec8e993</citedby><cites>FETCH-LOGICAL-c421t-4373ebd7738f23101c6b87f377bbfdc71bf14bb53f2fd687ad9e0179a5ec8e993</cites><orcidid>0000-0003-2738-2056 ; 0000-0002-2885-4839 ; 0000-0003-4415-3204</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/S0928493118326729$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,776,780,3537,27901,27902,65306</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/30678937$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>González-Ballesteros, Noelia</creatorcontrib><creatorcontrib>Rodríguez-Argüelles, M. Carmen</creatorcontrib><creatorcontrib>Prado-López, Sonia</creatorcontrib><creatorcontrib>Lastra, Mariano</creatorcontrib><creatorcontrib>Grimaldi, Maria</creatorcontrib><creatorcontrib>Cavazza, Antonella</creatorcontrib><creatorcontrib>Nasi, Lucia</creatorcontrib><creatorcontrib>Salviati, Giancarlo</creatorcontrib><creatorcontrib>Bigi, Franca</creatorcontrib><title>Macroalgae to nanoparticles: Study of Ulva lactuca L. role in biosynthesis of gold and silver nanoparticles and of their cytotoxicity on colon cancer cell lines</title><title>Materials Science & Engineering C</title><addtitle>Mater Sci Eng C Mater Biol Appl</addtitle><description>Marine bio-resources are being widely studied as an invaluable source of compounds with therapeutic applicability. In particular, macroalgae contain an extended variety of bioactive compounds with different structures and promising biological applications. In this work, Ulva lactuca L. (hereafter UL) was utilyzed for the synthesis of gold and silver nanoparticles. Full characterization by UV–Vis spectroscopy, TEM, HRTEM and STEM miscroscopies, Z Potential and FTIR spectroscopy was performed. The first time in the scientific literature, the composition of carbohydrates of UL extract and their changes observed after nanoparticles synthesis were explored in order to investigate their possible role in the biosynthetic process. The reducing power, total phenolic content and DPPH scavenging activity of UL extract, Au@UL and Ag@UL nanoparticles were determined. The effects of UL extract, Au@UL and Ag@UL were tested in vitro on the colon cancer cell lines HT-29 and Caco-2, on normal primary neonatal dermal fibroblast cell line PCS-201-010, as well as on normal colon cell line CCD-112CoN. Lastly, the apoptotic activity and cellular uptake evaluation was determined for Au@UL and Ag@UL.
•Aqueous extract of Ulva lactuca served to synthesize gold and silver nanoparticles.•The composition of the extract before and after the synthesis was determined.•This provided new information about the possible role of sugars during the synthesis.•The effects of UL extract, Au@UL and Ag@UL were tested in vitro on colon cancer cells.•Apoptotic activity and cellular uptake evaluation was determined for Au@UL and Ag@UL.</description><subject>AgNP</subject><subject>Algae</subject><subject>Antioxidants - chemistry</subject><subject>Apoptosis</subject><subject>Apoptosis - drug effects</subject><subject>AuNP</subject><subject>Bioactive compounds</subject><subject>Biocompatibility</subject><subject>Biosynthesis</subject><subject>Biotechnology</subject><subject>Caco-2</subject><subject>Cancer</subject><subject>Carbohydrates</subject><subject>Carbohydrates - analysis</subject><subject>Carbohydrates - chemistry</subject><subject>Cell Line, Tumor</subject><subject>Cell Proliferation - drug effects</subject><subject>Chemical compounds</subject><subject>Colon</subject><subject>Colon cancer</subject><subject>Colonic Neoplasms - metabolism</subject><subject>Colonic Neoplasms - pathology</subject><subject>Colorectal cancer</subject><subject>Cytotoxicity</subject><subject>Fourier transforms</subject><subject>Gold</subject><subject>Gold - chemistry</subject><subject>HT-29</subject><subject>Humans</subject><subject>Marine resources</subject><subject>Materials science</subject><subject>Metal Nanoparticles - chemistry</subject><subject>Metal Nanoparticles - toxicity</subject><subject>Microscopy, Electron, Transmission</subject><subject>Nanoparticles</subject><subject>Neonates</subject><subject>Pharmacology</subject><subject>Phenolic compounds</subject><subject>Phenols</subject><subject>Phenols - chemistry</subject><subject>Plant Extracts - chemistry</subject><subject>Scavenging</subject><subject>Seaweeds</subject><subject>Silver</subject><subject>Silver - chemistry</subject><subject>Skin</subject><subject>Spectrophotometry</subject><subject>Spectroscopy</subject><subject>Spectroscopy, Fourier Transform Infrared</subject><subject>Spectrum analysis</subject><subject>Toxicity</subject><subject>Tumor cell lines</subject><subject>Ulva - metabolism</subject><subject>Ulva lactuca</subject><issn>0928-4931</issn><issn>1873-0191</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2019</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kTuP1DAUhS0EYoeFP0CBLNHQJPiRxAmiWa14SYMoYGvLj5vFI4892M6I-Tf8VBxmQYKCxrfwd869Ogehp5S0lNDh5a7dZzAtI3RsKWvJMNxDGzoK3hA60ftoQyY2Nt3E6QV6lPOOkGHkgj1EF5wMYpy42KAfH5VJUflbBbhEHFSIB5WKMx7yK_y5LPaE44xv_FFhr0xZjMLbFqfoAbuAtYv5FMpXyC6v3G30FqtgcXb-COlvv18fFaq4S9icSizxuzOu1BUBm-jXVwVTdQa8x94FyI_Rg1n5DE_u5iW6efvmy_X7Zvvp3Yfrq21jOkZL03HBQVsh-DgzXuMxgx7FzIXQerZGUD3TTuuez2y2wyiUnYBQMakezAjTxC_Ri7PvIcVvC-Qi9y6vZ6gAccmSVbjr-7qgos__QXdxSaFeV6madk-6nlWKnamab84JZnlIbq_SSVIi1_7kTq79ybU_SZms_VXRszvrRe_B_pH8LqwCr88A1CyODpLMxkHNzLoEpkgb3f_8fwLIiq6K</recordid><startdate>20190401</startdate><enddate>20190401</enddate><creator>González-Ballesteros, Noelia</creator><creator>Rodríguez-Argüelles, M. Carmen</creator><creator>Prado-López, Sonia</creator><creator>Lastra, Mariano</creator><creator>Grimaldi, Maria</creator><creator>Cavazza, Antonella</creator><creator>Nasi, Lucia</creator><creator>Salviati, Giancarlo</creator><creator>Bigi, Franca</creator><general>Elsevier B.V</general><general>Elsevier BV</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QF</scope><scope>7QO</scope><scope>7QQ</scope><scope>7SC</scope><scope>7SE</scope><scope>7SP</scope><scope>7SR</scope><scope>7T7</scope><scope>7TA</scope><scope>7TB</scope><scope>7U5</scope><scope>8BQ</scope><scope>8FD</scope><scope>C1K</scope><scope>F28</scope><scope>FR3</scope><scope>H8D</scope><scope>H8G</scope><scope>JG9</scope><scope>JQ2</scope><scope>KR7</scope><scope>L7M</scope><scope>L~C</scope><scope>L~D</scope><scope>P64</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0003-2738-2056</orcidid><orcidid>https://orcid.org/0000-0002-2885-4839</orcidid><orcidid>https://orcid.org/0000-0003-4415-3204</orcidid></search><sort><creationdate>20190401</creationdate><title>Macroalgae to nanoparticles: Study of Ulva lactuca L. role in biosynthesis of gold and silver nanoparticles and of their cytotoxicity on colon cancer cell lines</title><author>González-Ballesteros, Noelia ; Rodríguez-Argüelles, M. Carmen ; Prado-López, Sonia ; Lastra, Mariano ; Grimaldi, Maria ; Cavazza, Antonella ; Nasi, Lucia ; Salviati, Giancarlo ; Bigi, Franca</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c421t-4373ebd7738f23101c6b87f377bbfdc71bf14bb53f2fd687ad9e0179a5ec8e993</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2019</creationdate><topic>AgNP</topic><topic>Algae</topic><topic>Antioxidants - chemistry</topic><topic>Apoptosis</topic><topic>Apoptosis - drug effects</topic><topic>AuNP</topic><topic>Bioactive compounds</topic><topic>Biocompatibility</topic><topic>Biosynthesis</topic><topic>Biotechnology</topic><topic>Caco-2</topic><topic>Cancer</topic><topic>Carbohydrates</topic><topic>Carbohydrates - analysis</topic><topic>Carbohydrates - chemistry</topic><topic>Cell Line, Tumor</topic><topic>Cell Proliferation - drug effects</topic><topic>Chemical compounds</topic><topic>Colon</topic><topic>Colon cancer</topic><topic>Colonic Neoplasms - metabolism</topic><topic>Colonic Neoplasms - pathology</topic><topic>Colorectal cancer</topic><topic>Cytotoxicity</topic><topic>Fourier transforms</topic><topic>Gold</topic><topic>Gold - chemistry</topic><topic>HT-29</topic><topic>Humans</topic><topic>Marine resources</topic><topic>Materials science</topic><topic>Metal Nanoparticles - chemistry</topic><topic>Metal Nanoparticles - toxicity</topic><topic>Microscopy, Electron, Transmission</topic><topic>Nanoparticles</topic><topic>Neonates</topic><topic>Pharmacology</topic><topic>Phenolic compounds</topic><topic>Phenols</topic><topic>Phenols - chemistry</topic><topic>Plant Extracts - chemistry</topic><topic>Scavenging</topic><topic>Seaweeds</topic><topic>Silver</topic><topic>Silver - chemistry</topic><topic>Skin</topic><topic>Spectrophotometry</topic><topic>Spectroscopy</topic><topic>Spectroscopy, Fourier Transform Infrared</topic><topic>Spectrum analysis</topic><topic>Toxicity</topic><topic>Tumor cell lines</topic><topic>Ulva - metabolism</topic><topic>Ulva lactuca</topic><toplevel>online_resources</toplevel><creatorcontrib>González-Ballesteros, Noelia</creatorcontrib><creatorcontrib>Rodríguez-Argüelles, M. Carmen</creatorcontrib><creatorcontrib>Prado-López, Sonia</creatorcontrib><creatorcontrib>Lastra, Mariano</creatorcontrib><creatorcontrib>Grimaldi, Maria</creatorcontrib><creatorcontrib>Cavazza, Antonella</creatorcontrib><creatorcontrib>Nasi, Lucia</creatorcontrib><creatorcontrib>Salviati, Giancarlo</creatorcontrib><creatorcontrib>Bigi, Franca</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Aluminium Industry Abstracts</collection><collection>Biotechnology Research Abstracts</collection><collection>Ceramic Abstracts</collection><collection>Computer and Information Systems Abstracts</collection><collection>Corrosion Abstracts</collection><collection>Electronics & Communications Abstracts</collection><collection>Engineered Materials Abstracts</collection><collection>Industrial and Applied Microbiology Abstracts (Microbiology A)</collection><collection>Materials Business File</collection><collection>Mechanical & Transportation Engineering Abstracts</collection><collection>Solid State and Superconductivity Abstracts</collection><collection>METADEX</collection><collection>Technology Research Database</collection><collection>Environmental Sciences and Pollution Management</collection><collection>ANTE: Abstracts in New Technology & Engineering</collection><collection>Engineering Research Database</collection><collection>Aerospace Database</collection><collection>Copper Technical Reference Library</collection><collection>Materials Research Database</collection><collection>ProQuest Computer Science Collection</collection><collection>Civil Engineering Abstracts</collection><collection>Advanced Technologies Database with Aerospace</collection><collection>Computer and Information Systems Abstracts Academic</collection><collection>Computer and Information Systems Abstracts Professional</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>Materials Science & Engineering C</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>González-Ballesteros, Noelia</au><au>Rodríguez-Argüelles, M. Carmen</au><au>Prado-López, Sonia</au><au>Lastra, Mariano</au><au>Grimaldi, Maria</au><au>Cavazza, Antonella</au><au>Nasi, Lucia</au><au>Salviati, Giancarlo</au><au>Bigi, Franca</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Macroalgae to nanoparticles: Study of Ulva lactuca L. role in biosynthesis of gold and silver nanoparticles and of their cytotoxicity on colon cancer cell lines</atitle><jtitle>Materials Science & Engineering C</jtitle><addtitle>Mater Sci Eng C Mater Biol Appl</addtitle><date>2019-04-01</date><risdate>2019</risdate><volume>97</volume><spage>498</spage><epage>509</epage><pages>498-509</pages><issn>0928-4931</issn><eissn>1873-0191</eissn><abstract>Marine bio-resources are being widely studied as an invaluable source of compounds with therapeutic applicability. In particular, macroalgae contain an extended variety of bioactive compounds with different structures and promising biological applications. In this work, Ulva lactuca L. (hereafter UL) was utilyzed for the synthesis of gold and silver nanoparticles. Full characterization by UV–Vis spectroscopy, TEM, HRTEM and STEM miscroscopies, Z Potential and FTIR spectroscopy was performed. The first time in the scientific literature, the composition of carbohydrates of UL extract and their changes observed after nanoparticles synthesis were explored in order to investigate their possible role in the biosynthetic process. The reducing power, total phenolic content and DPPH scavenging activity of UL extract, Au@UL and Ag@UL nanoparticles were determined. The effects of UL extract, Au@UL and Ag@UL were tested in vitro on the colon cancer cell lines HT-29 and Caco-2, on normal primary neonatal dermal fibroblast cell line PCS-201-010, as well as on normal colon cell line CCD-112CoN. Lastly, the apoptotic activity and cellular uptake evaluation was determined for Au@UL and Ag@UL.
•Aqueous extract of Ulva lactuca served to synthesize gold and silver nanoparticles.•The composition of the extract before and after the synthesis was determined.•This provided new information about the possible role of sugars during the synthesis.•The effects of UL extract, Au@UL and Ag@UL were tested in vitro on colon cancer cells.•Apoptotic activity and cellular uptake evaluation was determined for Au@UL and Ag@UL.</abstract><cop>Netherlands</cop><pub>Elsevier B.V</pub><pmid>30678937</pmid><doi>10.1016/j.msec.2018.12.066</doi><tpages>12</tpages><orcidid>https://orcid.org/0000-0003-2738-2056</orcidid><orcidid>https://orcid.org/0000-0002-2885-4839</orcidid><orcidid>https://orcid.org/0000-0003-4415-3204</orcidid></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0928-4931 |
| ispartof | Materials Science & Engineering C, 2019-04, Vol.97, p.498-509 |
| issn | 0928-4931 1873-0191 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_2179455773 |
| source | MEDLINE; Elsevier ScienceDirect Journals |
| subjects | AgNP Algae Antioxidants - chemistry Apoptosis Apoptosis - drug effects AuNP Bioactive compounds Biocompatibility Biosynthesis Biotechnology Caco-2 Cancer Carbohydrates Carbohydrates - analysis Carbohydrates - chemistry Cell Line, Tumor Cell Proliferation - drug effects Chemical compounds Colon Colon cancer Colonic Neoplasms - metabolism Colonic Neoplasms - pathology Colorectal cancer Cytotoxicity Fourier transforms Gold Gold - chemistry HT-29 Humans Marine resources Materials science Metal Nanoparticles - chemistry Metal Nanoparticles - toxicity Microscopy, Electron, Transmission Nanoparticles Neonates Pharmacology Phenolic compounds Phenols Phenols - chemistry Plant Extracts - chemistry Scavenging Seaweeds Silver Silver - chemistry Skin Spectrophotometry Spectroscopy Spectroscopy, Fourier Transform Infrared Spectrum analysis Toxicity Tumor cell lines Ulva - metabolism Ulva lactuca |
| title | Macroalgae to nanoparticles: Study of Ulva lactuca L. role in biosynthesis of gold and silver nanoparticles and of their cytotoxicity on colon cancer cell lines |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-01T02%3A15%3A35IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Macroalgae%20to%20nanoparticles:%20Study%20of%20Ulva%20lactuca%20L.%20role%20in%20biosynthesis%20of%20gold%20and%20silver%20nanoparticles%20and%20of%20their%20cytotoxicity%20on%20colon%20cancer%20cell%20lines&rft.jtitle=Materials%20Science%20&%20Engineering%20C&rft.au=Gonz%C3%A1lez-Ballesteros,%20Noelia&rft.date=2019-04-01&rft.volume=97&rft.spage=498&rft.epage=509&rft.pages=498-509&rft.issn=0928-4931&rft.eissn=1873-0191&rft_id=info:doi/10.1016/j.msec.2018.12.066&rft_dat=%3Cproquest_cross%3E2179455773%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2193150452&rft_id=info:pmid/30678937&rft_els_id=S0928493118326729&rfr_iscdi=true |