Prognostic roles of time to positivity of blood culture in children with Streptococcus pneumoniae bacteremia

We aimed to investigate the relationship between time to positivity (TTP) of blood cultures and clinical outcomes in children with S. pneumoniae bacteremia. Children with S. pneumoniae bacteremia hospitalized in Children’s Hospital of Chongqing Medical University from May 2011 to December 2017 were...

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Veröffentlicht in:	European journal of clinical microbiology & infectious diseases 2019-03, Vol.38 (3), p.457-465
Hauptverfasser:	Li, Qinyuan, Li, Yuanyuan, Yi, Qian, Suo, Fengtao, Tang, Yuan, Luo, Siying, Tian, Xiaoyin, Zhang, Guangli, Chen, Dapeng, Luo, Zhengxiu
Format:	Artikel
Sprache:	eng
Schlagworte:	Bacteremia Biomedical and Life Sciences Biomedicine Blood Blood culture Children Internal Medicine Mechanical ventilation Medical Microbiology Mortality Original Article Patients Risk analysis Risk factors Sepsis Septic shock Streptococcus infections Streptococcus pneumoniae Ventilation
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Zusammenfassung:	We aimed to investigate the relationship between time to positivity (TTP) of blood cultures and clinical outcomes in children with S. pneumoniae bacteremia. Children with S. pneumoniae bacteremia hospitalized in Children’s Hospital of Chongqing Medical University from May 2011 to December 2017 were enrolled retrospectively. Overall, 136 children with S. pneumoniae bacteremia were enrolled. The standard cutoff TTP was 12 h. We stated that in-hospital mortality is significantly higher in the early TTP (≤ 12 h) group than that in the late TTP (> 12 h) group (41.70% vs 8.00%, P
ISSN:	0934-9723 1435-4373
DOI:	10.1007/s10096-018-03443-5