Primary Osteosarcoma of the Breast: Pathophysiology and Imaging Review

Extraskeletal osteosarcoma are rare malignant mesenchymal neoplasms of soft tissues representing around 1% of all soft tissue. The exact mechanism of tumorigenesis of primary breast osteosarcoma is still unclear. However, most of the cases develop without a recognized etiologic factor. Primary osteo...

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Veröffentlicht in:Current problems in diagnostic radiology 2020-03, Vol.49 (2), p.116-123
Hauptverfasser: Mujtaba, Bilal, Nassar, Sameh M., Aslam, Rizwan, Garg, Naveen, Madewell, John E., Taher, Ahmed, Hanafy, Abdelrahman k., Whitman, Gary
Format: Artikel
Sprache:eng
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Zusammenfassung:Extraskeletal osteosarcoma are rare malignant mesenchymal neoplasms of soft tissues representing around 1% of all soft tissue. The exact mechanism of tumorigenesis of primary breast osteosarcoma is still unclear. However, most of the cases develop without a recognized etiologic factor. Primary osteosarcoma of the breast is often initially misdiagnosed as breast fibroadenoma. Different imaging modalities and pathology play important role in differentiating breast osteosarcoma from other benign and malignant lesions of the breast resulting in dramatic change in the management.
ISSN:0363-0188
1535-6302
DOI:10.1067/j.cpradiol.2019.01.001