Collapsing glomerulonephritis with podocyte markers in hemophagocytic syndrome secondary to hepatosplenic T-cell lymphoma

The hemophagocytic syndrome is a serious clinical-histological entity secondary to different diseases. Collapsing glomerulonephritis is a proliferative podocytopathy that usually has an unfavorable renal prognosis. We present a case in which both entities were associated, which is an infrequent form...

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Veröffentlicht in:Biomédica 2018-12, Vol.38 (4), p.456-462
Hauptverfasser: Martín-Gómez, María Adoración, Caba-Molina, Mercedes, Viciana-Martínez-Lage, María José, Ortega-Salas, Rosa, Sánchez-Crespo, Alicia, Soriano-Pérez, Manuel Jesús, Gómez-Morales, Mercedes
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Sprache:spa
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Zusammenfassung:The hemophagocytic syndrome is a serious clinical-histological entity secondary to different diseases. Collapsing glomerulonephritis is a proliferative podocytopathy that usually has an unfavorable renal prognosis. We present a case in which both entities were associated, which is an infrequent form of hepatosplenic T-cell lymphoma. In addition, we review the role of the markers of podocyte dedifferentiation in this glomerulopathy and its pathophysiology and treatment.
ISSN:0120-4157
DOI:10.7705/biomedica.v38i4.3893