Analysis of motor and respiratory function in Duchenne muscular dystrophy patients
•Duchenne muscular dystrophy patients presented motor and respiratory deterioration.•Non-ambulatory condition was associated with worse motor function measure and spirometry.•Deterioration of motor and respiratory function showed correlation between each other.•The assessments should be performed on...
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Veröffentlicht in: | Respiratory physiology & neurobiology 2019-04, Vol.262, p.1-11 |
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Format: | Artikel |
Sprache: | eng |
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Zusammenfassung: | •Duchenne muscular dystrophy patients presented motor and respiratory deterioration.•Non-ambulatory condition was associated with worse motor function measure and spirometry.•Deterioration of motor and respiratory function showed correlation between each other.•The assessments should be performed on a routine basis.
Duchenne muscular dystrophy(DMD) shows motor and respiratory impairment.
19 DMD patients (DMDG) (nine ambulatory and 10 non-ambulatory) were evaluated through motor function measure (MFM), 6-minute walk test (6MWT), respiratory muscle strength, cough peak flow, spirometry and volumetric capnography (VCap) tools. Control group that performed spirometry and VCap (CG1-n = 17) were different from those that performed the 6MWT (CG2-n = 8).
The follow tools were assessed (p |
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ISSN: | 1569-9048 1878-1519 |
DOI: | 10.1016/j.resp.2019.01.009 |