The impact of implant abutment surface treatment with TiO2 on peri-implant levels of angiogenesis and bone-related markers: a randomized clinical trial

The impact of implant abutment surface treatment with TiO2 on peri-implant levels of angiogenesis and bone-related markers: a randomized clinical trial

The goal of this randomized, blinded, split-mouth controlled clinical trial was to assess the influence of abutment surface treatment on tissue healing. Fifteen patients received two implants distributed randomly to two groups: test (TiO2 abutment surface), control (standard abutment surface). Level...

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Veröffentlicht in:International journal of oral and maxillofacial surgery 2019-07, Vol.48 (7), p.962-970
Hauptverfasser: Óbice, A.L.S., Correa, M.G., Feng, H.S., Ribeiro, F.V., Cirano, F.R., Casati, M.Z., Pimentel, S.P.
Format: Artikel
Sprache:eng
Schlagworte:
biological markers
bone
dental abutment
dental implants
protein array
surface treatment
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Zusammenfassung:The goal of this randomized, blinded, split-mouth controlled clinical trial was to assess the influence of abutment surface treatment on tissue healing. Fifteen patients received two implants distributed randomly to two groups: test (TiO2 abutment surface), control (standard abutment surface). Levels of epidermal growth factor (EGF), bone morphogenetic protein 9 (BMP-9), endothelin 1 (ET-1), fibroblast growth factor (FGF), placental growth factor (PlGF), and vascular endothelial growth factor (VEGF) were quantified in the peri-implant fluid after 3, 14, 30, and 60 days. Inter-group comparisons indicated higher levels of EGF, BMP-9, ET-1, FGF, and PlGF in the test group after 30days (P
ISSN:0901-5027
1399-0020
DOI:10.1016/j.ijom.2018.12.012