Dipeptidyl peptidase-4 inhibitors: Anti-diabetic drugs with potential effects on cancer

Dipeptidyl peptidase-4 inhibitors: Anti-diabetic drugs with potential effects on cancer

Dipeptidyl peptidase (DPP- 4) inhibitors belong to the oral antidiabetic drugs. They are used for the treatment of Type 2 Diabetes mellitus. DPP-4 is an enzyme which puts down the action of hormone, incretin. Incretins belong to the group of hypoglycaemic gastrointestinal hormones. Some studies show...

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Veröffentlicht in:Diabetes & metabolic syndrome clinical research & reviews 2019-01, Vol.13 (1), p.36-39
Hauptverfasser: Almagthali, Alaa G., Alkhaldi, Eman H., Alzahrani, Afnan S., Alghamdi, Ameera K., Alghamdi, Waleed Y., Kabel, Ahmed M.
Format: Artikel
Sprache:eng
Schlagworte:
Cancer
Diabetes mellitus
Dipeptidyl peptidase-4 inhibitors
Patients
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Zusammenfassung:Dipeptidyl peptidase (DPP- 4) inhibitors belong to the oral antidiabetic drugs. They are used for the treatment of Type 2 Diabetes mellitus. DPP-4 is an enzyme which puts down the action of hormone, incretin. Incretins belong to the group of hypoglycaemic gastrointestinal hormones. Some studies show that DPP-4 inhibitors causes cancer and some study show that they have anticancer property. This review sheds light on the role of the different types of DPP-4 inhibitors in cancer therapy.
ISSN:1871-4021
1878-0334
DOI:10.1016/j.dsx.2018.08.012