Pneumococcal meningitis before the introduction of 10-valent pneumococcal conjugate vaccine into the National Childhood Immunization Program in Poland

Pneumococcal meningitis before the introduction of 10-valent pneumococcal conjugate vaccine into the National Childhood Immunization Program in Poland

•Reported incidence of pneumococcal meningitis increased in persons ≥15 years of age.•PCV10 and PCV13 serotypes accounted for 46% and 62% of all isolates, respectively.•Proportion of cases caused by PCV10 serotypes decreased from 2008 to 2011 to 2012-2015.•The average penicillin resistance of all is...

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Veröffentlicht in:Vaccine 2019-02, Vol.37 (10), p.1365-1373
Hauptverfasser: Polkowska, Aleksandra, Skoczyńska, Anna, Paradowska-Stankiewicz, Iwona, Stefanoff, Paweł, Hryniewicz, Waleria, Kuch, Alicja, Lyytikäinen, Outi, Nuorti, J. Pekka
Format: Artikel
Sprache:eng
Schlagworte:
Age
Antimicrobial agents
Antimicrobial resistance
Cefotaxime
Cerebrospinal fluid
Children
Conjugates
Demographics
Disease
Epidemiology
Fatalities
Health surveillance
Immunization
Laboratories
Meningitis
Penicillin
Pneumococcal conjugate vaccine, PCV10
Pneumococcal meningitis
Population
Public health
Serotypes
Statistical tests
Streptococcus infections
Streptococcus pneumoniae
Surveillance
Trends
Vaccines
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Beschreibung
Zusammenfassung:•Reported incidence of pneumococcal meningitis increased in persons ≥15 years of age.•PCV10 and PCV13 serotypes accounted for 46% and 62% of all isolates, respectively.•Proportion of cases caused by PCV10 serotypes decreased from 2008 to 2011 to 2012-2015.•The average penicillin resistance of all isolates amounted 28%.•Among children
ISSN:0264-410X
1873-2518
DOI:10.1016/j.vaccine.2018.12.028