Clinical efficacy of herbal extract cream on the skin hydration, elasticity, thickness, and dermis density for aged skin: A randomized controlled double‐blind study

Summary Background Traditional medicine herbal prescriptions used for the treatment of skin disease have been developed into cosmetics. Sang‐Hyul‐Yun‐Boo‐Em (SHYBE) is a mixed herbal formula prescribed for patients with yin or blood deficiency patterns of skin disease. A previous study reported that SHYBE exercises anti‐allergic and anti‐inflammatory effects. To date, no study has reported the efficacy of cosmetics containing the SHYBE extract. Aims To observe the efficacy of SHYBE extract cream on hydration, elasticity, thickness, and dermis density in aged skin. Methods This was a double‐blind randomized placebo‐controlled parallel‐group trial. The trial consisted of an 8‐week topical application of the test or placebo products with two visits at 4‐week intervals. A total of 46 healthy Korean females, aged 40‐59, were enrolled in this study. Objective skin assessments for hydration, elasticity, thickness and dermis density, self‐assessment, and safety assessment were conducted. Results Sang‐Hyul‐Yun‐Boo‐Em extract cream improved skin hydration, elasticity, and dermal density in Asian middle‐aged females compared with placebo cream, which excluded SHYBE extract and contained other cosmetic materials. Conclusions Sang‐Hyul‐Yun‐Boo‐Em extract cream showed anti‐aging properties in middle‐aged women. It could be recommended for aging skin with dryness, and loss of elasticity and density.