Comparative outcomes in patients with ulcer‐ vs non‐ulcer‐related acute upper gastrointestinal bleeding in the United Kingdom: a nationwide cohort of 4474 patients

Summary Background Outcomes after Nonvariceal upper gastrointestinal bleeding (NVUGIB) have historically focused on ulcer‐related causes. Little is known regarding non‐ulcer bleeding, the most common cause of NVUGIB. Aim To compare outcomes between ulcer‐ and non‐ulcer‐related NVUGIB and explore whether these could be explained by differences in baseline characteristics, bleeding severity or processes of care. Methods Analysis of 4474 patients with NVUGIB from 212 United Kingdom hospitals as part of a nationwide audit. Logistic regression models were used to adjust for baseline characteristics, bleeding severity and processes of care. Results 1682 patients had ulcer‐related and 2792 patients had non‐ulcer‐related bleeding. Those with ulcer‐related bleeding were older (median age 73 vs 69, P