Assessing functional connectivity of brain network in children with nocturnal enuresis using resting state functional magnetic resonance imaging

[10],[11],[12] Nocturnal Enuresis and Resting State Functional Magnetic Resonance Imaging Lei et al.,[11],[12] have studied the changes in spontaneous brain activity in children with primary monosymptomatic nocturnal enuresis (PMNE) using statistical parametric mapping (SPM) and a resting-state fMRI data analysis toolkit (REST). [...]the correlation of temporal signal fluctuations in one cerebral region with another region could potentially mimic true inter- connected neuronal activation (as seen in the case of blood flow). [...]our goal should be to sample the brain activity utilizing layer-specific high resolution sampling using a high-field MRI platform, with cutting edge techniques like the multiband echo-planar imaging with a low repetition times (of less than 0.5 sec) with an optimal permissible specific absorption rate.