BNP: Is it an ideal marker to assess volume status in patients with hyponatremia and natriuresis?

A number of variables affect plasma brain natriuretic peptide and N-terminal pro brain natriuretic peptide levels, including the assay used, age (higher normal values are observed with increasing age), sex (higher values are observed in women), body mass index (lower levels are observed with a higher body mass index) renal dysfunction, inflammatory conditions, steroid therapy and diurnal variation. [...]for correction of hyponatremia, fluid restriction is needed in SIADH and fluid repletion is required in CSW. The presence of an “extreme” CVP value may be more helpful to guide in fluid administration than the presence of intermediate values. [...]the correlation of CVP