Risk factors for loss of skeletal muscle mass in patients with cirrhosis

Risk factors for loss of skeletal muscle mass in patients with cirrhosis

Aim The present study aimed to assess the correlation between loss of skeletal muscle mass (LSMM) and the clinical characteristics of patients with liver cirrhosis. Methods This multicenter, prospective study was undertaken at five locations in Japan and involved a 12‐month observation period. After...

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Veröffentlicht in:Hepatology research 2019-05, Vol.49 (5), p.550-558
Hauptverfasser: Sung, Ji Hyun, Uojima, Haruki, Hidaka, Hisashi, Tanaka, Yoshiaki, Wada, Naohisa, Kubota, Kousuke, Nakazawa, Takahide, Shibuya, Akitaka, Fujikawa, Tomoaki, Yamanoue, Hiroki, Kako, Makoto, Koizumi, Wasaburo
Format: Artikel
Sprache:eng
Schlagworte:
Cirrhosis
Hepatic encephalopathy
Liver cirrhosis
liver fibrosis
malnutrition
Multivariate analysis
Musculoskeletal system
Risk factors
Skeletal muscle
WFA+‐M2BP
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Beschreibung
Zusammenfassung:Aim The present study aimed to assess the correlation between loss of skeletal muscle mass (LSMM) and the clinical characteristics of patients with liver cirrhosis. Methods This multicenter, prospective study was undertaken at five locations in Japan and involved a 12‐month observation period. After baseline assessment, the change in the skeletal muscle index per year (ΔSMI/y) was evaluated in the enrolled patients; LSMM was defined as ΔSMI/y 
ISSN:1386-6346
1872-034X
DOI:10.1111/hepr.13308