Thyroid Function in Patients With a Fontan Circulation

In this study, we tested our hypothesis that thyroid function is impaired and contributes to perturbed hemodynamics in patients after Fontan operation. Cardiac catheterization and blood tests for thyroid function were performed in 37 patients who underwent a Fontan operation. Among them, 12 patients...

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Veröffentlicht in:	The American journal of cardiology 2019-03, Vol.123 (6), p.979-983
Hauptverfasser:	Kuwata, Seiko, Takanashi, Manabu, Hashimoto, Megumi, Iwamoto, Yoichi, Ishido, Hirotaka, Masutani, Satoshi, Saiki, Hirofumi, Sugamoto, Kenji, Senzaki, Hideaki
Format:	Artikel
Sprache:	eng
Schlagworte:	Blood Brain Brain natriuretic peptide Cardiac Catheterization Cardiac output Catheterization Child Congestion Correlation Female Follow-Up Studies Fontan Procedure Heart Heart Defects, Congenital - blood Heart Defects, Congenital - complications Heart Defects, Congenital - surgery Heart surgery Hemodynamics Hemodynamics - physiology Humans Hypothyroidism Hypothyroidism - blood Hypothyroidism - complications Intubation Laboratories Liver Male Patients Postoperative Period Relaxation time Retrospective Studies Surgery Thyroid Thyroid gland Thyroid Gland - metabolism Thyroid hormones Thyroid-stimulating hormone Thyroxine Thyroxine - blood Time constant Triiodothyronine Triiodothyronine - blood Ventricle
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Beschreibung
Zusammenfassung:	In this study, we tested our hypothesis that thyroid function is impaired and contributes to perturbed hemodynamics in patients after Fontan operation. Cardiac catheterization and blood tests for thyroid function were performed in 37 patients who underwent a Fontan operation. Among them, 12 patients (33%) had subclinical thyroid dysfunction with an elevated thyroid-stimulating hormone level despite normal thyroxine levels. Thyroid-stimulating hormone levels were significantly correlated with central venous pressure (p
ISSN:	0002-9149 1879-1913
DOI:	10.1016/j.amjcard.2018.12.005