Would immunization be the same without cross-reactivity?

Would immunization be the same without cross-reactivity?

Highlights•Cross-reactivity is common and important from a public health perspective. •Real-world cross-protection data against non-vaccine types are now available. •Clinical and economic impact assessments should include cross-protective effects of vaccine.

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Bibliographische Detailangaben
Veröffentlicht in:Vaccine 2019-01, Vol.37 (4), p.539-549
Hauptverfasser: Vojtek, Ivo, Buchy, Philippe, Doherty, T. Mark, Hoet, Bernard
Format: Artikel
Sprache:eng
Schlagworte:
Adjuvants
Adjuvants, Immunologic
Allergy and Immunology
Animals
Antigens
Avian flu
Clinical trials
Clinical Trials as Topic
Cross Protection
Cross Reactions
Cross-reactivity
Disease
Drug delivery systems
Epitopes
Homology
Human papillomavirus
Humans
Immune response
Immune system
Immunization
Immunostimulation
Microorganisms
Pathogens
Proteins
Reactivity
Smallpox
Streptococcus infections
Surveillance
Tuberculosis
Vaccines
Vaccines - immunology
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Beschreibung
Zusammenfassung:Highlights•Cross-reactivity is common and important from a public health perspective. •Real-world cross-protection data against non-vaccine types are now available. •Clinical and economic impact assessments should include cross-protective effects of vaccine.
ISSN:0264-410X
1873-2518
DOI:10.1016/j.vaccine.2018.12.005