Light/Palladium‐Promoted Benzylic C−H Acylation Using a Benzoyl Group as the Photo‐Directing Group

Light/Palladium‐Promoted Benzylic C−H Acylation Using a Benzoyl Group as the Photo‐Directing Group

2‐Methylphenyl ketones undergo site‐selective acylation at the benzylic position when treated with acid anhydride under UV irradiation in the presence of a palladium catalyst. The benzoyl carbonyl group serves as the photo‐directing group so that the ortho benzylic C−H bond is activated site‐selecti...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Chemistry, an Asian journal an Asian journal, 2019-02, Vol.14 (3), p.403-406
Hauptverfasser: Masuda, Yusuke, Ishida, Naoki, Murakami, Masahiro
Format: Artikel
Sprache:eng
Schlagworte:
Acidic oxides
Acylation
Anhydrides
Carbonyl groups
Carbonyls
Chemistry
C−H activation
directing group
Hydrogen bonds
Ketones
Palladium
photoreaction
Ultraviolet radiation
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:2‐Methylphenyl ketones undergo site‐selective acylation at the benzylic position when treated with acid anhydride under UV irradiation in the presence of a palladium catalyst. The benzoyl carbonyl group serves as the photo‐directing group so that the ortho benzylic C−H bond is activated site‐selectively. Lightning Bolt! 2‐Methylphenyl ketones undergo site‐selective acylation at the benzylic position when treated with acid anhydride under UV irradiation in the presence of a palladium catalyst. The benzoyl carbonyl group serves as the photo‐directing group so that the ortho benzylic C−H bond is activated site‐selectively.
ISSN:1861-4728
1861-471X
DOI:10.1002/asia.201801881