Outcomes of Early-Onset Acute Type A Aortic Dissection　― Influence of Etiologic Factors

Outcomes of Early-Onset Acute Type A Aortic Dissection　― Influence of Etiologic Factors

Background: Outcomes of early-onset acute type A aortic dissection (ATAAD) associated with Marfan syndrome (MFS) are known, but not with other etiologies. Methods and Results: ATAAD patients from 2 centers (n=1,001) were divided into 2 groups: age ≤45 years (n=93) and age >45 years (n=908). Altho...

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Veröffentlicht in:Circulation Journal 2019/01/25, Vol.83(2), pp.285-294
Hauptverfasser: Kimura, Naoyuki, Aizawa, Kei, Kawahito, Koji, Itagaki, Ryo, Yamaguchi, Atsushi, Misawa, Yoshio, Siepe, Matthias, Czerny, Martin, Beyersdorf, Friedhelm, Kari, Fabian Alexander, Rylski, Bartosz
Format: Artikel
Sprache:eng
Schlagworte:
Acute Disease
Adult
Age Factors
Aged
Aorta, Thoracic - growth & development
Aorta, Thoracic - pathology
Aortic Aneurysm, Thoracic - etiology
Aortic Aneurysm, Thoracic - mortality
Aortic Aneurysm, Thoracic - surgery
Aortic dissection
Aortic Dissection - etiology
Aortic Dissection - mortality
Aortic Dissection - surgery
Aortic Valve - abnormalities
Aortic Valve - pathology
Aortic Valve - surgery
Bicuspid Aortic Valve Disease
Early onset
Female
Heart Valve Diseases - pathology
Heart Valve Diseases - surgery
Humans
Hypertension
Male
Marfan Syndrome
Middle Aged
Non-syndromic familial thoracic aortic aneurysm and dissection
Retrospective Studies
Survival Analysis
Treatment Outcome
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Zusammenfassung:Background: Outcomes of early-onset acute type A aortic dissection (ATAAD) associated with Marfan syndrome (MFS) are known, but not with other etiologies. Methods and Results: ATAAD patients from 2 centers (n=1,001) were divided into 2 groups: age ≤45 years (n=93) and age >45 years (n=908). Although in-hospital death and 10-year survival were similar (12% vs. 7% and 62.6% vs. 67.3%), the 10-year aortic event-free survival differed (50.0% vs. 80.2%; P
ISSN:1346-9843
1347-4820
1347-4820
DOI:10.1253/circj.CJ-18-0969