Validation of the eighth edition AJCC staging system in early T1 to T2 oral squamous cell carcinoma

Background To validate the newly proposed American Joint Committee on Cancer (AJCC) eighth edition staging in early T1 and T2 oral cavity cancers and its effect in predicting tumour control. Methods Retrospective analysis of treatment outcomes of 441 T1 to T2 oral squamous cell carcinoma (OSCC). Ove...

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Veröffentlicht in:	Journal of surgical oncology 2019-03, Vol.119 (4), p.449-454
Hauptverfasser:	Murthy, Samskruthi, Low, Tsu‐Hui (Hubert), Subramaniam, Narayana, Balasubramanian, Deepak, Sivakumaran, Vidhyadharan, Anand, Adharsh, Vijayan, Smitha Nalumackal, Nambiar, Ajit, Thankappan, Krishnakumar, Iyer, Subramania
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged American Joint Committee for Cancer 8 Cancer surgery depth of invasion Female Humans Male Middle Aged Mouth Neoplasms - mortality Mouth Neoplasms - pathology Neoplasm Staging Oral cancer Retrospective Studies Squamous cell carcinoma Squamous Cell Carcinoma of Head and Neck - mortality Squamous Cell Carcinoma of Head and Neck - pathology Tongue tongue cancer Tumors
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Zusammenfassung:	Background To validate the newly proposed American Joint Committee on Cancer (AJCC) eighth edition staging in early T1 and T2 oral cavity cancers and its effect in predicting tumour control. Methods Retrospective analysis of treatment outcomes of 441 T1 to T2 oral squamous cell carcinoma (OSCC). Overall survival (OS), disease‐specific survival (DSS), and tumour control were calculated and compared between the AJCC 7 and 8 staging systems. Results The 5‐year OS was 78% and 61% for T1 and T2 tumours, respetively (P
ISSN:	0022-4790 1096-9098
DOI:	10.1002/jso.25348